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Title: Application of hair analysis concerning selected psychoactive substances for medico - legal purposes

Abstract:

The present experimental investigations were inspired by the necessity of standardizing the procedures and analytical methods employed in hair analysis aiming at a retrospective evaluation of ingestion of various xenobiotics. Thus, in keeping with the principal premises, the main objective of the thesis was development of unique, novel chemico-toxicological procedures for analyzing the hair content of psychoactive substances in four basic groups of substances of abuse: opioids (morphine, 6-monoacetylmorphine, codeine, methadone and its metabolite - EDDP), amphetamines (amphetamine, methamphetamine, MDA, MDMA, MDEA), cocaine and its metabolites (benzoiloecgonine and cocaethylene) by HPLC-APCI-MS-MS and cannabinoids (∆9-THC and cannabinol) by GC-EI-MS-MS , followed by verification of the thus worked out procedures in medico-legal practice through opinionating in selected groups of cases: participants in methadone substitution therapy (abstinence control), teenage abusers of psychoactive substances (medical diagnosis) and patients deceased due to fatal psychoactive substance poisoning (cause of death determination).

Level of degree:

2 - studia doktoranckie

Degree discipline:

toksykologia ; medycyna sądowa

Degree grantor:

Wydział Lekarski

Promoter:

Małgorzata Kłys

Date issued:

2009

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:926

Call number:

ZB-110717

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Access rights:

tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego - Collegium Medicum

Object collections:

Last modified:

Sep 12, 2019

In our library since:

Nov 21, 2012

Number of object content hits:

8

Number of object content views in PDF format

8

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/926

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ZB-110717 Sep 12, 2019
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