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Title: Therapeutic and prognostic importance of pelvic lymph nodes metastasis in operative endometrial carcinoma

Abstract:

The objective of paper is to evaluate the frequency of metastasis to pelvic lymph nodes in endometrial cancer; determine the correlation between occurrence of metastasis to pelvic lymph nodes and selected clinical morphological factors; determine prognostic importance of metastasis to pelvic lymph nodes and determine the correlation between 5-year survival of the patients and selected clinical and morphological factors. This study was based on data obtained from 183 women with endometrial carcinoma operated in Chair of Gynecology&Oncology CMUJ. Subjects were divided into 2 groups. Group I was operated using simple hysterectomy. Group II was operated using expanded hysterectomy with removal of pelvic lymph nodes. Based on the observations and obtained results we came to the following conclusions: incidence of pelvic lymph node metastasis in endometrial carcinoma involves 19,27% of cases and worsen 5-year survival rate. There is a correlation between metastasis to regional pelvic lymph nodes and histological type, grading, depth of invasion and the presence of estrogen receptors. Besides the clinical grade, other histo-morphological factors mentioned above, which correlate with the proportion of lymph node metastasis i.e. histology of the tumor, its maturity grade, cell tumor arrangement, depth of malignant invasion of the myometrium and the presence of estrogen receptors, have an effect on 5-year survival rates. Radical hysterectomy with removal of pelvic lymph nodes, in comparison to simple hysterectomy, it significantly decreases the proportion of postoperative radiotherapy.

Level of degree:

2 - studia doktoranckie

Degree discipline:

onkologia ; ginekologia

Degree grantor:

Wydział Lekarski

Promoter:

Antoni Basta

Date issued:

2009

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:894

Call number:

ZB-109884

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Access rights:

tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego - Collegium Medicum

Object collections:

Last modified:

Nov 19, 2019

In our library since:

Nov 21, 2012

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All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/894

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ZB-109884 Nov 19, 2019
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