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Title: Caregivers’ health-related quality of life in Alzheimer’s disease

Abstract:

Objectives: The aim of this study was to evaluate different aspects of AD caregiver’s quality of life, burden, family relationship (EE) in longitudal study in relation to dementia stage. Method: The study included 79 pairs comprising patients with AD and their respective family caregivers. The study was conducted between January 2008 and March 2010 in specialized outpatient memory clinic (Department of Psychiatry) in Cracow using a ICD-10 research criteria. Sociodemographic variables were obtained and the following questionnaires were administered: the 36-Item Short-Form Health Survey (SF-36), the Polish Questionnaire of Caregivers Burden in Dementia (DCBI), Five Minute Speech Sample (FMSS) and Beck Depression Inventory (BDI). Subjects with AD were evaluated with following tests: the Washington Clinical Dementia Rating (CDR) and Mini-Mental Status Examination (MMSE). Neuropsychiatric Inventory (NPI) was used to collect information of patients’behavioral symptoms (BPSD). Three subgroups were selected for this study with regard to the intensity of dementia process, estimated according to the Washington Clinical Dementia Rating (CDR). Both patients and caregivers were assessed at 3 points over a 12-month period: after 2 weeks, after 6 months from first examination and after 12 months from first examination. Results: Finally after 12 months, 63 pairs of AD patients and their caregivers were studied. It was stated that the quality of life experienced by caregivers depends significantly on the stage of disease according to CDR. It was shown that the caregivers with high EE and depression experience the lower quality of life. There was a positive correlation between the BPSD and perceived burden. The significant predictors of caregivers depression were higher NPI score and high EE. The depression was less common in caregivers of subjects with mild AD. Conclusion: Caregivers of Alzheimer’s patient suffer a negative impact on their health-related quality of life (HRQoL). The quality of life of caregivers is correlated with the severity of the Alzheimer's disease, BPSD, caregivers’ depression and EE.

Level of degree:

2 - studia doktoranckie

Degree discipline:

psychiatria

Degree grantor:

Wydział Lekarski

Promoter:

Andrzej Zięba

Date issued:

2010

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:845

Call number:

ZB-113864

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Access rights:

tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego - Collegium Medicum

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Last modified:

Oct 15, 2019

In our library since:

Nov 21, 2012

Number of object content hits:

21

Number of object content views in PDF format

21

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/845

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ZB-113864 Oct 15, 2019
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