Object

Title: Evaluation of the risk of prostatic urethral infiltration by prostate cancer in patients undergoing laparoscopic radical prostatectomy

Abstract:

Aim of the study: Based on the assumption that the risk of urethral invasion is low at patients with organ-confined prostate cancer, The aims of this prospective study were as follows: ● Assessment of the feasibility of dissection of the prostatic urethra from the prostatic tissue ● Assessment of the cancer invasion in the urethra● Evaluation of the risk factors associated with the cancer invasion into the urethra Conclusions: 1. In a group of 88 patients, the prostatic urethra was effectively removed ex vivo from all of the postoperative specimens. It was found that the dissection of this part of the urethra without leaving the remnants of the prostate gland is not technically feasible. 2. In 11 cases (12,5%), cancer cells were detected within the dissected prostatic urethra. 3. There was correlation between the invasion of the prostatic urethra and the following preoperative clinical characteristics: higher PSA level, greater local extent of the disease assessed clinically (cT) 4. There was correlation between the invasion of the prostatic urethra and the following pathologic parameters: greater local extent of the disease after pathologic staging (pT),invasion of perineural tissue within the tumour 5. The results of this study provide foundation for further research involving modification of laparoscopic radical prostatectomy technique, which is aimed prostatic urethra preservation in order to reduce the rate of the postoperative urinary incontinence.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

urologia ; onkologia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Piotr Chłosta ; Tomasz Gołąbek

Date issued:

2017

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:4243

Call number:

ZB-128096

ControlNumberVIRTUA:

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Language:

pol

Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

Object collections:

Last modified:

May 13, 2019

In our library since:

May 10, 2018

Number of object content hits:

306

Number of object content views in PDF format

309

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4244

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ZB-128096 May 13, 2019
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