Object

This publication is protected and available only for logged users.
This publication is protected and available only for logged users.

Title: The importance of direct tissue autofluorescence imaging and selected proinflammatory cytokines in oral squamous cell carcinoma and oral potentially malignant disorders diagnostics

Abstract:

Oral squamous cell carcinoma (OSCC) is a serious and growing problem in many parts of the globe. Sometimes it is preceded by oral potentially malignant disorders (OPMD). Unfortunately many cases of OSCC are diagnosed at the late stage what leads to very low survival rate. The aim of the study was to evaluate the usefulness of the direct autofluorescence visualization technique (VELscope®) and proinflammatory cytokines (IL-1α, IL-6, IL-8 and TNF-α) in OSCC and OPMD diagnostics. The study proved that VELscope® could be useful in OSCC and OPMD diagnostics. Its sensitivity in identification of OSCC and dysplasia was higher but specificity was lower in comparison with conventional oral examination. The results showed, that VELscope® could be recommended as a screening tool among patients with OSCC history. The salivary level of IL-1α, IL-6, IL-8 and TNF-α was significantly higher in patients with OSCC in comparison to healthy controls, and IL-6, IL-8 and TNF-α also in comparison with patients with OPMD without dysplasia.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

stomatologia ; onkologia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Maria Chomyszyn-Gajewska

Date issued:

2016

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:4140

Call number:

ZB-125994

ControlNumberVIRTUA:

click here to follow the link

Language:

pol

Access rights:

tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

Object collections:

Last modified:

May 24, 2021

In our library since:

Mar 13, 2017

Number of object content hits:

4

Number of object content views in PDF format

4

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4140

Show description in RDF format:

RDF

Show description in OAI-PMH format:

OAI-PMH

Edition name Date
ZB-125994 May 24, 2021
×

Citation

Citation style:

This page uses 'cookies'. More information