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Title: Long term results of percutaneous coronary intervention with the useof drug eluting balloon in patients with coronary artery disease

Abstract:

Introduction Since the 1970's, when the first percutaneous coronary intervention (PCI) wasperformed, this method has undergone a distinct evolution. In turn the effectiveaction of locally administered drugs has contributed to the development of theconcept of a antimitotic drug-eluting balloon (DEB).AimsThe goal of this study was to analyze the long-term results of PCI with DEB incorrelation with the clinical and angiographic characteristics of the treated patientsand the treatment strategy.ResultsA total of 112 patients were included in the study. The population was thendivided into two groups, A (40%) consisted of patients with target vessel failure(TVF), B (60%) without TVF. The study group was comprised mainly of patients inthe sixth decade of life that had been qualified for the invasive treatment of unstableangina. Male patients dominated. More than half of the patients were active smokerswith a history of myocardial infarction.The differences between study groups were observed in relation to the followingfactors: differences in severity of heart failure (NYHA III and IV A 32%, B 13%,p=0.0479), previous PCI (A 19.4%, B 4.3%, p=0.0423), treated lesion length (A19.4 mm, B 16.1 mm, p=0.0166), predilatation with standard balloon (A 60%, B33%, p=0.0119), residual stenosis (A 20%, B 17%, p=0.0341).Regression model showed independent risk factors affecting the prognosis:severity of heart failure (p = 0.0250; OR 1.34-33.23) and initial length of the treatedlesion (p = 0.0273, OR 1.02-1.30)ConclusionsPCI with the use of a DEB is a safe method to treat patients diagnosed withischemic heart disease. The results of investigated strategy can be significantly betterin the treatment of shorter lesions in patients without signs of heart failure, and inthis group should be taking into consideration, especially in case of contraindicationsfor DES.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia ; kardiochirurgia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Krzysztof Żmudka

Date issued:

2012

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:3647

Call number:

ZB-119608

ControlNumberVIRTUA:

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Language:

pol

Access rights:

tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

Object collections:

Last modified:

Jun 26, 2019

In our library since:

Jan 9, 2014

Number of object content hits:

8

Number of object content views in PDF format

8

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/3647

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ZB-119608 Jun 26, 2019
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