Object

Title: Using of botulinum toxin type A (BTX-A) in treatment of spasticity of the lower limbs in children with cerebral palsy

Abstract:

INTRODUCTION Through researches followed there is no significant correlation between type and intensity of rehabilitation during treatment with BTX-A. Positive results of treatment with BTX-A shows many of the prospective and retrospective trials. OBJECTIVES: The trial was undertaken under consideration to clarify differences between control and injection group and the measure of efficiency of treatment after serial doses of BTX-A. MATERIAL AND METHODS: Children with cerebral palsy were allocated to control group- 165 and injection group- 173 cases. Outcome measure included the Modified Ashworth Scale (MAS), ROM (range of motion), MFIM test, Global Clinical Impression (GCI). RESULTS: The results confirms that the treatment with BTX- A depends on age, dose, interval between injections, type of paralysis, as well as the time and place of rehabilitation. The statistically relevant determinants of chances for improvements were the methods and the place. The chance of improvement increased four times with NDT therapy and three times in rehabilitation center. CONCLUSIONS: The most effective improvement of motion after BTX-A treatment was observed in children with diplegia and hemiplegia walking without aids.Patients without required rehabilitation (5 cases, due to social reasons), after using BTX-A presented even worse results than at the baseline. Permanent and neurodevelopmental rehabilitation is a condition of using BTX-A in children with CP.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

neurologia ; rehabilitacja ; pediatria

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Antoni Czupryna

Date issued:

2011

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:3466

Call number:

ZB-117069

ControlNumberVIRTUA:

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Language:

pol

Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

Object collections:

Last modified:

May 24, 2021

In our library since:

Mar 8, 2013

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Number of object content views in PDF format

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All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/3466

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ZB-117069 May 24, 2021
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