This publication is unavailable to your account. If you have more privileged account please try to use it or contact with the institution connected to this digital library.
Korpanty, Grzegorz
2005
Praca doktorska
The study demonstrates the non-invasive and selective delivery of a gene of human vascular endothelial growth factor (VEGF) using non-viral vector (plasmid) to rat myocardium using ultrasound targeted microbubbles destruction techinque (UTMD). Expression of delivered gene was restricted to the UTMD targeted organ. There was a significant increase in arteriolar density in animals, that received control plasmid with luciferase gene. This finding is probably due to non-specific effects of UTMD on microcirculation and expression of genes that promote arteriogenesis. The exact molecular mechanism of this phenomenon together with the impact of UTMD- stimulated arteriogenesis on coronary blood flow remains to be determined.
Kraków
2 - studia doktoranckie
choroby układu krążenia ; biologia molekularna
Wydział Lekarski
Adamek-Guzik, Teresa
oai:dl.cm-uj.krakow.pl:1294
ZB-100453
pol
nieograniczony
Jun 26, 2023
Nov 21, 2012
425
58
http://dl.cm-uj.krakow.pl:8080/publication/1294
RDF
OAI-PMH
Citation style: chicago-author-date iso690-author-date
This page uses 'cookies'. More information I understand