Object

Title: The prognostic value of heart biopsy zero after its transplantation

Abstract:

The heart transplantation is a popular and general method of therapy in difficult heart diseases in advanced stages of a circulatory insufficing. The most important role of the heart transplantation plays the qualification of suitability of the donor and recipient’s heart, the immunosupressive therapy after the transplantation, the protection and the therapy of infection. The heart donors are usualy the young people with recognized brain deaths, mostly after a craniocerebral trauma, with the efficiency cardiovascular system. The total ischemic time ( the time from clamping of the donor aorta during harvesting to unclamping of the recipient aorta after aortic anastomosis) ranged below 4-6 h. The aim of the research was the histologic investigation of the zero biopsies obtained from donor hearts before and during the transplantation. The evaluation of the prognosis of the zero biopsies in the heart’s donor within the investigation of the postransplanted process. The investigation of the influence of the ischemic time over the state of postransplanted heart. The material – biopsy specimens was collected from 105 heart of donor aged 15-46 years. The biopsy 0-1 was obtained during an organ procurement and the biopsy 0-2 - immediately before a coronary reperfusion after the transplantation. The histological investigation was done by the light microscope. The most important conclusion of the work: the morphological picture of the myocardium in the zero biopsy has an effect on the postransplantation process.

Level of degree:

2 - studia doktoranckie

Degree discipline:

patomorfologia ; transplantologia ; kardiochirurgia

Degree grantor:

Wydział Lekarski

Promoter:

Romana Tomaszewska

Date issued:

2006

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:1138

Call number:

ZB-105627

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Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego - Collegium Medicum

Object collections:

Last modified:

Jun 24, 2019

In our library since:

Nov 21, 2012

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All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/1138

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ZB-105627 Jun 24, 2019
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