Title: Prophylaxis of venous thromboembolism in medical inpatients of Hospital in Rabka-Zdroj


The objective of this study was to evaluate the efficacy and safety of two models of thromboprophylaxis with nadroparine in medical inpatients of Rabka-Zdroj Hospital.The study was performed as an open-label randomized trial.A total of 300 patients were randomly assigned to two groups in proportion 1:1.In the first group patients received thromboprophylaxis with nadroparine only during the period of bed immobilization, in the second group for 10 days longer.The follow-up lasted for the three months after the end of thromboprophylaxis.Proximal deep veins thrombosis of lower limbs and death were considered as endpoints.Adverse effects of nadroparine were assessed, especially major bleedings and thrombocytopenia.During the time of thromboprophylaxis there were neither deaths nor major bleedings in both groups.During the 3-month follow-up of all the 300 enrolled patients in 17 (5,6%) of them endpoints were found.Two patients suddenly died and in 15 patients the evidence of deep venous thrombosis of lower limbs was found.During the 3-month follow-up there were no major bleeedings or thrombocytopenia.In one patient mild allergic symptoms in the place of heparine iniection was observed.The study confirmed the effectiveness and safety of thromboprophylaxis with nadroparine in medical inpatients.In patients receiving thromboprophylaxis longer than during the immobilization period the endpoints were observed less frequently.

Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia

Degree grantor:

Wydział Lekarski


Anetta Undas

Date issued:






Call number:



click here to follow the link

Access rights:


Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego - Collegium Medicum

Object collections:

Last modified:

Jun 24, 2019

In our library since:

Nov 21, 2012

Number of object content hits:

2 489

Number of object content views in HTML format


All available object's versions:


Show description in RDF format:


Show description in OAI-PMH format:


Edition name Date
ZB-105504 Jun 24, 2019


Citation style:

This page uses 'cookies'. More information