Tytuł:

Efficacy assessment of combined dye - radioactive technique in sentinel lymph node identification in breast cancer

Autor:

Basta, Paweł

Temat i słowa kluczowe:

sentinel lymph node ; breast cancer

Abstrakt:

Sentinel lymph node (SLN) mapping in breast cancer patients could spare some of them axillary lymphadenectomy. The present study was designed to assess the efficacy of SLN biopsy by using a combination of two techniques: the dye and the radioactive, with subcutaneus periareolar tracer injection. 80 women, aged 33-79 year, with primary, invasive breast cancer, less than 5 cm, and clinically negative loco-regional lymph nodes were entered into the study. Identification rate of SLN was 88,8 %. Efficacy of SLN detection by the method used in the study was calculated on the basis of pathological reports of dissected lymph nodes. Sensitivity was 89,3 %, negative predictive value - 93,5 %, and false negative rate 10,7 %. In conclusion, the mapping of breast lymphatic system by using two techniques: the dye and the radioactive, with subcutaneus periareolar tracer injection, is an effective method of SLN detection in breast cancer patients. Statistical analysis demonstrated that out of clinical and pathological features considered, only surgical excisional biopsy may negatively affect the SLN identification rate.

Miejsce wydania:

Kraków

Stopień studiów:

2 - studia doktoranckie

Dyscyplina:

ginekologia ; onkologia ; chirurgia

Instytucja nadająca tytuł:

Wydział Lekarski

Promotor:

Nowak, Wojciech

Data:

2007

Data wydania:

2007

Typ:

Praca doktorska

Sygnatura:

ZB-107315

Język:

pol

Prawa dostępu:

nieograniczony