Aim: The aim of the study was to assess the course of gastro-esophageal reflux disease (GERD) in children. Methods: We included to the study 200 children (44% females and 56% males) diagnosed with GERD on the basis of positive result of 24-hour pH-monitoring (fT≥4.2%). Median age at the time of diagnosis amounted to 4.5 year (from 1 month to 17.5 year). After a mean period of 2 years from the diagnosis, the guardians or patients filled in a questionnaire evaluating past and present GERD symptoms. Additionally, the control pH-monitoring was conducted in 71 patients. The patients, who initially presented with gastrointestinal GERD symptoms (163 children) were divided into three age groups, considering the time of the diagnosis: group I - below 1 year of age (38 children), group II - between 1 and 4 years of age (35 children) and group III - above 4 years of age (90 children). Results: The gastrointestinal GERD symptoms disappeared completely in 45%, 14.3% and 13.3% of patients from group I, II, and III, respectively. The presence of feeding problems below 1 year of age was found to be a risk factor of persistent GERD symptoms (p=0.007; LR(Likehood ratio)=8.9). In 38 patients (54% of the study group) the control pH-monitoring revealed pathologic acid reflux (fT>4.2%). The epigastric pain was found to be a risk factor of positive result of the control 24-hour pH-monitoring. (p=0.01 ; 72, OR=3.32; CI=1.21-8.60). Conclusion: In children above 1 year of age a complete disappearance of GERD symptoms is observed very rarely.
Mar 10, 2023
Nov 21, 2012
|ZB-106440||Mar 10, 2023|
Kędra,Edyta (red nauk ). Kowalak,Czesław (współpraca)