Advanced search ?

Object

Access Limited

This publication is protected and can be accessed only from certain IPs.
This publication is protected and can be accessed only from certain IPs.

Title: Circulation of early hematopoetic, muscle, cardiac, and endothelial tissue-commited stem cell during myocardial infarction

Author:

Michałowska-Kaczmarczyk, Anna

Date:

2007

Type:

Praca doktorska

Abstract:

It is assumed that small number of tissue-specific progenitor cells circulate in peripheral blood and the intensified mobilization of the cells from tissue niches, mainly from bone marrow, occurs during acute myocardial infarction. An increase in the number of circulating CD34+, CD117+, c-met+ and CXCR4+ cells in peripheral blood during early period of acute myocardial infarction has been indicated from results of the tests. Simultaneously, a growth in expression of mRNA for cardiac, muscular and endothelial markers among circulating mononuclear cells has been observed. Intensified mobilization of hematopoetic progenitors has been stated in clonogenic in vitro tests. The results of the tests confirmed the hypothesis assuming that the stress involved with myocardial infarction mobilizes tissue-derived stem cells–from tissue niches to peripheral blood. Mobilization of the cells is accompanied by some changes in cytokine concentration in peripheral blood (an increase in VEGF, IL-6, G-CSF and HGF, and a decrease in serum level of SDF-1). The results obtained in the dissertation suggest not only the possibility of circulation of heterogenic population of stem cells in blood but also confirmed the mobilization induced by organ damage in the course of myocardial infarction.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia ; fizjologia ; transplantologia

Degree grantor:

Wydział Lekarski

Promoter:

Ratajczak, Mariusz

Date issued:

2007

Identifier:

oai:dl.cm-uj.krakow.pl:950

Call number:

ZB-106436

Language:

pol

Access rights:

tylko w bibliotece

Subject and keywords:

myocardial infarction stem cell

Object collections:

Last modified:

Feb 4, 2023

In our library since:

Nov 21, 2012

Number of object content hits:

13

Number of object content views in PDF format

0

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/950

Show description in RDF format:

RDF

Show description in OAI-PMH format:

OAI-PMH

Edition name Date
ZB-106436 Feb 4, 2023

Objects

Similar

Circulation of early hematopoetic, muscle, cardiac, and endothelial tissue-commited stem cell during myocardial infarction

Michałowska-Kaczmarczyk, Anna

2007
Praca doktorska

Mobilization of stem cells into the peripheral blood in children with congenital heart disease

Borówka, Magdalena

2017
Praca doktorska

Immunohistochemical diagnosis of early myocardial infarction in postmortem medico-legal examination

Rzepecka-Woźniak, Ewa

2007
Praca doktorska

Comparison of clinical outcomes, echocardiographic changes and prognosis in patients with myocardial infraction with or without ST elevation in whom angiography revealed occlusion/significant stenosis of the left circumflex/obtuse marginal artery

Grzymała-Lubańska, Joanna

2016
Praca doktorska

Arginine and its metabolites in acute myocardial infarction

Mołek-Dziadosz, Patrycja

2023
Praca doktorska

Effectiveness of manual aspiration thrombectomy in selected angiographic indications and in subgroups of patients with ST-segment elevation myocardial infraction

Wojdyła, Roman

2020
Praca doktorska

Detailed characteristic of stem cells isolated from Wharton's Jelly (WJ-MSCs) by use of modern molecular genetic methods

Musiał-Wysocka, Aleksandra

2020
Praca doktorska

Myocardial infarction with non-obstructive coronary arteries. The selected aspects of pathogenesis, diagnosis, treatment and the impact on long-term prognosis

Stępień, Konrad

2023
Praca doktorska
More
×

Citation

Citation style:

Contact details

Address

Medical Library
Medyczna 7
30-688 Krakow

Phone

12 658 72 56
517 385 669

E-Mail

Collecting and Elaboration Department
cyfrowabm@cm-uj.krakow.pl

Visit us!

This page uses 'cookies'. More information