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Tytuł: Structure and function of left ventricle and large arteries in adult normotensive offspring of hypertensive patients

Autor:

Loster, Magdalena

Data:

2009

Typ:

Praca doktorska

Abstrakt:

On the basis of data collected in the family – based study we performed the analysis of relationship between positive family history of hypertension and structure and function of left ventricle and large arteries in offspring. The study population was recruited during the continuation of European Project on Genes in Hypertension (EPOGH). The study population consisted of 290 subjects: 141 parents and 115 their offspring mean age 28 years. The standardized questionnaire, conventional blood pressure measurements, ambulatory blood pressure monitoring, complete echocardiographic evaluation, ultrasound measurements of intima – media thickness and pulse wave analysis were performed. Normotensive adult offspring of hypertensive parents have higher diastolic blood pressure on conventional measurements as well as on ambulatory monitoring than normotensive adult offspring of normotensive parents. Significant differences in conventional parameters of left ventricular diastolic function was observed: lower E/A ratio and longer isovolumetric relaxation time independently of blood pressure levels. Offspring of hypertensive parents had higher peripheral and central augmentation index. These results may indicate the potential role of hereditary factors in the development of diastolic dysfunction and large arteries dysfunction in hypertension.

Miejsce wydania:

Kraków

Stopień studiów:

2 - studia doktoranckie

Dyscyplina:

choroby układu krążenia

Instytucja nadająca tytuł:

Wydział Lekarski

Promotor:

Kawecka-Jaszcz, Kalina

Data wydania:

2008

Identyfikator:

oai:dl.cm-uj.krakow.pl:905

Sygnatura:

ZB-110216

Język:

pol

Prawa dostępu:

nieograniczony

Temat i słowa kluczowe:

offspring arterial stiffness left ventricular function intima-media thickness hypertension

Kolekcje, do których przypisany jest obiekt:

Data ostatniej modyfikacji:

26 cze 2023

Data dodania obiektu:

21 lis 2012

Liczba wyświetleń treści obiektu:

546

Liczba wyświetleń treści obiektu w formacie PDF

190

Wszystkie dostępne wersje tego obiektu:

http://dl.cm-uj.krakow.pl:8080/publication/905

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Wyświetl opis w formacie OAI-PMH:

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Nazwa wydania Data
ZB-110216 26 cze 2023

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Adres

Biblioteka Medyczna
ul. Medyczna 7
30-688 Kraków

Telefon

12 658 72 56
517 385 669

E-Mail

Oddział Gromadzenia i Opracowania Zbiorów
cyfrowabm@cm-uj.krakow.pl

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