Object

Title: Estimation of stature in children born with intrauterine growth retardation

Abstract:

In the world medical literature there are significant discrepancies concerning the percentage of children born with intrauterine growth retardation (IUGR), and also the percentage of children with short stature [below (-2) SDS] during preadolescence, and adolescence. In Polish literature there are no data referring to this topic. Short stature children exhibit low self-esteem, worse grades at school, and often also feel isolated from peer group, while in adult life they appear to be less successful in their jobs than normal-height persons. The remedy for those children is successfully attained in majority of cases by treatment with recombinant human growth hormone. The mentioned treatment is therefore applied in many countries and is planned to be introduced in our country in forthcoming years. Hence, in order to investigate the extent of short stature problem in IUGR and to identify the responsible factors, we have conducted the first survey in our country. The survey encompassed 414 preadolescent children (aged 6-9) out of 562 born with IUGR (< 10 centile) and 1000 randomly selected (500 girls and 500 boys) children out of 8108 individuals with body mass appropriate for gestational age ( 10 centile). The survey excluded children with other than IUGR causes of growth disorders. It was demonstrated that IUGR affects 6.6% of live birth children. Conclusions: 1. Around 9.5% children born with IUGR exhibits short stature, i.e. below (-2) SDS and below average height of parents, during preadolescence age. This represents an almost three-fold increase in comparison to children with body mass appropriate for gestational age. 2. Over 90% of children born with IUGR reach correct stature during preadolescence time, consistent with their parental height that is not different from the stature of children with body mass appropriate for gestational age. 3. Factors that predispose to short stature during preadolescence among children born with IUGR are stimulants used by mothers during pregnancy, such as smoking tobacco and drinking alcohol, as well as increasing parity and residing in rural areas during pregnancy. Factors such as duration of pregnancy, maternal age and parental height were found to be not significant from the examined material.

Level of degree:

2 - studia doktoranckie

Degree discipline:

pediatria

Degree grantor:

Wydział Lekarski

Promoter:

Jerzy Starzyk

Date issued:

2008

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:878

Call number:

ZB-109866

ControlNumberVIRTUA:

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Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego - Collegium Medicum

Object collections:

Last modified:

Sep 3, 2019

In our library since:

Nov 21, 2012

Number of object content hits:

485

Number of object content views in PDF format

483

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/878

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ZB-109866 Sep 3, 2019
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