Object
Title: Contrast-induced nephropathy in patients undergoing angiography and angioplasty procedures
Abstract:
Contrast-induced nephropathy (CIN) is a serious complication after exposure to iodinated contrast media. Recent studies show that N-acetylcysteine may play a significant role in prevention of CIN. The aim of his study was to evaluate the incidence of contrast-induced nephropathy in patients undergoing angiography and/or angioplasty procedures, to asses the efficacy of intravenous N-acetylcysteine in prevention of this complication and to asses the long term adverse effects of contrast-induced nephropathy. Results: Contrast-induced nephropathy was observed in 18,4% patients undergoing angiography and/or angioplasty procedures. The incidence of CIN was significantly reduced in patients receiving intravenous N-acetylcysteine as compared to patients receiving hydration with normal saline alone. The search for independent risk factors of contrast-induced nephropathy was performed. This revealed the following predictors: diabetes mellitus and impaired renal function (with eGFR < 60 ml/min/1,72m²), heart failure and volume of contrast medium administered. The risk of CIN was reduced in patients administered isoosmolal contrast medium. Probability of survival free of the following adverse events : cardiovascular death, heart infarct, dialysis, rehospitalization due to cardiac or renal causes was reduced in patients with contrast-induced nephropathy. Conclusions: The rate of long-term a ; dverse events was higher in patients with contrast-induced nephropathy. Administration of intravenous N-acetylcysteine reduces the risk of CIN.
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Last modified:
Mar 13, 2023
In our library since:
Nov 21, 2012
Number of object content hits:
11
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All available object's versions:
http://dl.cm-uj.krakow.pl:8080/publication/826
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| Edition name | Date |
|---|---|
| ZB-113634 | Mar 13, 2023 |
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