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Title: Procalcitonin as a diagnostic tool in vertical transmission sespis

Author:

Ferek, Justyna

Date:

2010

Type:

Praca doktorska

Abstract:

Procalcitonin was recently put forward as a diagnostic tool of systemic bacterial infection and sepsis in children and adults. The value of this marker during the first days of life is controversial. In analysis among 345 neonates procalcitonin serum concentration during the first 12 hours of life is higher than those in adults. None of analyzed perinatal complications affected procalcitonin serum concentration during the first 12 hours of life. Lower calcium levels are correlated with procalcitonin serum concentration elevation in non – infected group. PCT serum concentration during the first 12 hours of life plays an important role in diagnosing early-onset clinical sepsis and sepsis. In congenital pneumonia the PCT serum concentration wasn’t higher than those in non-infected group. Higher, but not significantly, serum procalcitonin concentration was observed in Gram-negative sepsis than in Gram-positive sepsis. There was no correlation between serum procalcitonin concentration and sepsis complications like multiorgan dysfunction, septic shock and death. PCT serum concentration sensitivity is higher compared to WBC, PLT, CRP concentration sensitivity. No significant differences in expression of human leucocyte antigen (HLA-DR), CD14 and CD16 on monocytes between groups with infection and non-infected neonates were observed. There was also no correlation between PCT concentration and expression of human leucocyte antigen (HLA-DR), CD14 and CD16 antigens on monocytes.

Level of degree:

2 - studia doktoranckie

Degree discipline:

pediatria

Degree grantor:

Wydział Lekarski

Promoter:

Ryszard Lauterbach

Date issued:

2009

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:807

Call number:

ZB-113475

ControlNumberVIRTUA:

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Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego - Collegium Medicum

Subject and keywords:

procalcitonin sepsis neonate

Object collections:

Last modified:

Oct 8, 2019

In our library since:

Nov 21, 2012

Number of object content hits:

1 255

Number of object content views in PDF format

1253

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/807

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Edition name Date
ZB-113475 Oct 8, 2019

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