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This publication is protected and can be accessed only from certain IPs.

Title: Incidence of subclinical hormonal activity and malignancy in patients with incidentally discovered adrenal tumors

Abstract:

An adrenal incidentaloma is defined as a mass lesion found unexpectedly in an adrenal gland by an imaging procedure performed for reasons other than suspected adrenal pathology. The aim of the study was to estimate the incidence of subclinical hormonal activity and malignancy among patients with incidentally discovered adrenal tumors. 413 patients with adrenal incidentaloma were involved into the study. The adrenal incidentaloma were found mainly in women at the age of 50 to 60. The incidence of the malignant tumors depends on the tumor size and increased at the tumor size of 40 mm, with significantly increased frequency at the size of 60 mm. Metastases were confirmed in 2,2% of patients, the most common primary site was kidney. The progression of tumor size after one year of observation was found in 25,8% of patients. The achieved results showed the better sensitivity of the morning cortisol level < 1,8 g/dl in overnight dexamethasone test for diagnosing hipercorticism, found in 9% of patients with adrenal incidentaloma. The measurement of fractionated urine metanephrines had the high sensitivity with low specificity for diagnosing phecochromocytoma. 45,5% of patients with confirmed primary aldosteronism had normal serum potassium levels.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

endokrynologia

Degree grantor:

Wydział Lekarski

Promoter:

Gołkowski, Filip

Date issued:

2009

Identifier:

oai:dl.cm-uj.krakow.pl:774

Call number:

ZB-111783

Language:

pol

Access rights:

tylko w bibliotece

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Last modified:

Mar 10, 2023

In our library since:

Nov 21, 2012

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0

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/774

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ZB-111783 Mar 10, 2023
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