Title:

Learning curve analysis for resections of primary and metastatic liver malignancies in terms of patient’s safety

Author:

Banaś, Bartłomiej

Subject:

Hepatocelurar carcinoma ; intrahepatic cholangiocarcinoma ; liver resection ; ovarian cancer

Abstract:

Background. Hepatocellurar carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and liver metastases require surgical treatment. Aim. Learning curves evaluation for liver resections. Material and Methods. A retrospective analysis of liver resections using cumulative sum control charts (CUSUM). Results. 362 cases were eligible for the analyses: 82 (22,65%) with primary liver malignancies were assigned to the Cohort 1, 158 (43,65%) with liver metastases of the colorectal cancer were allocated to the Cohort 2 and 122 (33,70%) women with stage IIIC ovarian cancer with or without liver involvement comprised the Cohort 3.The learning curves for major liver resections due to primary and metastatic tumors are comparable. Small liver resections were performed faster and with less intraoperative blood loss levels with shorter postoperative stays, and fewer complications. Fewer procedures were needed to gain stabilization and repeatability in operating times and intraoperative blood loss levels in small liver resections compared to major liver resections. Wedge liver resection performed as a part of cytoreductive surgery in women with advanced ovarian cancer can be performed safely and feasibly by gynecologic oncologists and does not increase the risk of surgical complications, nor significantly affects operating time, intraoperative blood loss or postoperative hospital stay.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree grantor:

Rada Dyscypliny Nauki medyczne

Promoter:

Kołodziejczyk, Piotr

Date:

2022

Date issued:

2022

Type:

Praca doktorska

Call number:

ZB-136291

Language:

pol; eng

Access rights:

nieograniczony