Novel markers of renal impairment in multiple myeloma patients - Digital Medical Library

Skip to main menu
Skip to search engine
Skip to content
Skip to footer

Download

This publication is protected and can be accessed only from certain IPs.

This publication is protected and can be accessed only from certain IPs.

Description
Information

Title: Novel markers of renal impairment in multiple myeloma patients

Author:

Woziwodzka, Karolina

Date:

Type:

Praca doktorska

Abstract:

Renal impairment (RI) in multiple myeloma (MM) affects 50% patients, leads to increased morbidity. The aim of this study was to evaluate the utility of markers: IGFBP-7, TIMP-2, transgelin-2 and monomer NGAL in MM, the influence of neoplasm on their concentrations and interactions between them. The follow-up data included serum creatinine, eGFR, the date and cause of death. Elevated serum and urine levels of these biomarkers were observed. The urine concentration of monomer NGAL, IGFBP-7 and serum concentration of transgelin-2 correlated with the decrease of eGFR and higher disease stage. They may be considered predicative of future chronic kidney disease. Majority of tubular biomarkers correlate with one another; however transgelin-2 seems to be an independent marker. The early measurement of these biomarkers in MM patients allows to predict the development of chronic kidney injury. The idea of creation of biomarkers panels seems to be superior in future development of their use.

Place of publishing:

Level of degree:

2 - studia doktoranckie

Degree discipline:

hematologia ; nefrologia

Degree grantor:

Rada Dyscypliny Nauki medyczne

Promoter:

Krzanowska, Katarzyna

Date issued:

Identifier:

oai:dl.cm-uj.krakow.pl:4951

Call number:

Language:

Access rights:

tylko w bibliotece

Subject and keywords:

multiple myeloma renal impairment tubular markers of kidney injury

Object collections:

Digital Medical Library > PhD thesis database

Last modified:

Mar 25, 2024

In our library since:

Feb 28, 2023

Number of object content hits:

0

Number of object content views in PDF format

0

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4952

Show description in RDF format:

Show description in OAI-PMH format:

Edition name	Date
ZB-136329	Mar 25, 2024

Objects

Similar

Novel markers of renal impairment in multiple myeloma patients

Woziwodzka, Karolina

2022

Praca doktorska

Assessment of ferric management in multiple myeloma in relationship to stage of kidney failure

Banaszkiewicz, Małgorzata

2022

Praca doktorska

Polskie Stowarzyszenie Pomocy Chorym na Szpiczaka

strona internetowa; forum

Myeloma Euronet : europejska sieć grup pacjentów chorych na szpiczaka

portale; stowarzyszenia

Powikłania zakrzepowo-zatorowe oraz inne zaburzenia hemostazy w szpiczaku mnogim

Undas, Anetta

nagranie video

Cytokiny w patogenezie szpiczaka mnogiego

Jurczyszyn, Artur

2003

Praca doktorska

Występowanie i przebieg kliniczny rabdomiolizy w wybranych populacjach terapeutycznych

Rakus, Anna

2004

Praca doktorska

Long-term follow-up in patients with an episode of acute renal failure

Walatek, Bogusław

2007

Praca doktorska

More

Citation style:

Contact details

Address

Medical Library
Medyczna 7
30-688 Krakow

Phone

12 658 72 56
517 385 669

E-Mail

Collecting and Elaboration Department
cyfrowabm@cm-uj.krakow.pl

Visit us!

https://bm.cm.uj.edu.pl/en/main-page/

This page uses 'cookies'. More information