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Title: Socioeconomic and health determinates of respiratory function and mortality due to respiratory diseases in adults

Abstract:

Objectives: The main purpose of this study was to assess the relationship between lung functions and mortality from respiratory diseases, and socioeconomic factors and cardiovascular disease risk factors. Methods: Data from the Polish part of the HAPIEE Study and data from routine statistics of Central Statistical Office were used. In the HAPIEE Study, 4104 men and women, who provided valid measurement of FEV 1 and FVC were included into the analysis. Exposure to CVD risk factors were assessed for all participants and total cardiovascular risk was assessed using SCORE function (Systematic COronary Risk Evaluation). SES in childhood and adulthood was determined by cluster analysis. In the ecological study,in each of the 66 sub-regions of Poland, standardized mortality rates were calculated for respiratory diseases. SES index was derived from the characteristic of the sub-regions using z-score methods. The linear regression and the analysis of covariance were the main statistical methods used. Results: In the Polish part of the HAPIEE Study, diabetes, obesity and hypertension were associated with lung functions. A significant negative trend was observed in the mean FEV1 and FVC values by SCORE categories. There were no significant associations between hypercholesterolemia and FEV 1 and FVC. After adjustment for potential confounders, SES in adulthood (both sexes) and SES in ; childhood (women) were significantly associated with respiratory functions. Higher SES was associated with higher average FVC and FEVl. Upward social mobility and moderate or high SES both at childhood and at adulthood were significantly related to higher FEV1 and FVC compared with low SES both at childhood and at adulthood or downward social mobility. The ecological study in 66 sub-regions of Poland, showed that SES, and an increase in SES over time were related to a decrease in mortality from respiratory disease. Conclusion: At the population level, SES and its change were significantly associated with mortality from respiratory diseases. At the individual level, higher SES in adulthood was associated with better respiratory function in men and women, while the relationship between SES in childhood and respiratory function was significant only in women. High life course SES in both childhood and adulthood, and an increase in SES between childhood and adulthood was associated with better respiratory function in adulthood. Impaired respiratory function was associated with a higher cardiovascular risk, which may be pardy explained by the inverse relationship between lung function and obesity, hypertension and diabetes.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

epidemiologia ; pulmonologia ; choroby układu krążenia

Degree grantor:

Rada Dyscypliny Nauki o zdrowiu

Promoter:

Pająk, Andrzej ; Szafraniec, Krystyna

Date issued:

2019

Identifier:

oai:dl.cm-uj.krakow.pl:4686

Call number:

ZB-132523

Language:

pol; eng

Access rights:

tylko w bibliotece

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Last modified:

Apr 8, 2024

In our library since:

May 23, 2022

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http://dl.cm-uj.krakow.pl:8080/publication/4687

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ZB-132523 Apr 8, 2024
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