Object

This publication is protected and can be accessed only from certain IPs.
This publication is protected and can be accessed only from certain IPs.

Title: Analysis of the airway remodeling in patients with asthma-chronic obstructive pulmonary disease overlap

Abstract:

The objective of the study was to assess the structural changes of the airways using endobronchial ultrasound (EBUS) and based on histopathological analysis of endobronchial biopsies in patients with asthma-chronic obstructive pulmonary disease overlap (ACO) compared to patients with severe asthma and chronic obstructive pulmonary disease (COPD). The study included 17 patients with ACO, 17 patients with COPD and 33 patients with severe asthma who underwent spirometry, bodyplethysmography, bronchoscopy with EBUS, bronchoalveolar lavage and endobronchial biopsies. Images were chosen from the movie recorded during bronchoscopy with EBUS based on which the total thickness of the bronchial wall and its particular layers were assessed. Histopathological evaluation of endobronchial biopsies and cytological analysis of bronchoalveolar lavage fluid were performed. Patients with ACO do not have a characteristic pattern of airway remodeling in histopathological examination of endobronchial biopsies, but have more severe changes in the airways assessed by the EBUS compared to patients with COPD, and less severe compared to patients with severe asthma. The thickness of bronchial wall and its particular layers in EBUS did not correlate with the results of histopathological examination of endobronchial biopsies in patients with ACO.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree grantor:

Wydział Lekarski

Promoter:

Soja, Jerzy

Date issued:

2020

Identifier:

oai:dl.cm-uj.krakow.pl:4679

Call number:

ZB-133506

Language:

pol

Access rights:

tylko w bibliotece

Object collections:

Last modified:

May 23, 2022

In our library since:

May 23, 2022

Number of object content hits:

0

Number of object content views in PDF format

0

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4680

Show description in RDF format:

RDF

Show description in OAI-PMH format:

OAI-PMH

Edition name Date
ZB-133506 May 23, 2022
×

Citation

Citation style:

This page uses 'cookies'. More information