Interim PET/CT response evaluation of advance Hodgkin Lymphoma (HL) - Digital Medical Library

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Title: Interim PET/CT response evaluation of advance Hodgkin Lymphoma (HL)

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Type:

Praca doktorska

Abstract:

In the response to treatment in Hodgkin's disease one may observe the shrinkage of the neoplastic lesions as well as normalization of 18-FDG uptake in their topography. The study examines the usefulness of various assessment methods of the PET/CT performed early after the introduction of treatment in 58 patients with advanced disease (interim), treated with a regimen starting with escBEACOPP, in case of a good response de-escalated to ABVD. The treatment regimen resulted in 88,3% OS and 83,3 % PFS after median 10,2 years of follow-up. Combination of the PET and CT criteria allowed to increase PPV while maintaining high NPV (86% and 96.1% respectively vs. 50% and 97.7% compared PET criteria alone). Additional information allowing to distinguish people with progression or recurrence of the disease were the ratio of SUV changes to liver SUV (expressed as rPET or qPET), metabolic tumour volume (MTV) in the interim PET, as well as the change of SUV between baseline and interim exams.

Place of publishing:

Level of degree:

2 - studia doktoranckie

Degree discipline:

Degree grantor:

Wydział Lekarski

Promoter:

Jurczak, Wojciech

Date issued:

Identifier:

oai:dl.cm-uj.krakow.pl:4675

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Subject and keywords:

Hodgkin Lymphoma PET/CT response evaluation interim exam escBEACOPP

Object collections:

Digital Medical Library > PhD thesis database

Last modified:

Jun 26, 2023

In our library since:

May 23, 2022

Number of object content hits:

90

Number of object content views in PDF format

105

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4676

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Edition name	Date
ZB-134101	Jun 26, 2023

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