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This publication is protected and can be accessed only from certain IPs.

Title: Long term observation of adults after coarctation of aorta repair in childhood

Abstract:

Coarctation of the aorta (CoA) is present in 4 in 10 000 live births, accounting for 5- 8% of all congenital heart diseases. Due to surgical correction, the survival rate of 30 years is nearly 74%. Only a few studies have described long-term observation of patients after CoA repair. The aim of the study, based on 3 original publications, was to describe and analyze long-term follow-up of patients after CoA correction. 58 consecutive adult patients after repaired CoA in childhood, being in the care of the Department of Congenital Heart Diseases in the John Paul II Hospital in Krakow, were included. The control group consisted of ageand sex-matched healthy volunteers. Clinical evaluation was performed by reviewing data from echocardiography, 24- hours ambulatory blood pressure measurement, cardiopulmonary exercise testing and non-invasive assessment of arterial stiffness. Among CoA patients more frequent were: arterial hypertension, hyperlipidemia, higher fasting glucose level and inflammatory markers: hsCRP and fibrinogen. Patients after the CoA correction had lower peak oxygen uptake (p<0.001), peak heart rate, duration of the test and peak workload (p<0.001). CoA patients presented higher central arterial stiffness parameters (AP, AIx , p<0.001). Patients after CoA repair in longer follow- up are exposed to arterial hypertension, recurrent aortic steno ; sis, aneurysms formation and premature atherosclerosis.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree grantor:

Wydział Lekarski

Promoter:

Tomkiewicz-Pająk, Lidia

Date issued:

2020

Identifier:

oai:dl.cm-uj.krakow.pl:4628

Call number:

ZB-132973

Language:

pol; eng

Access rights:

tylko w bibliotece

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Last modified:

Jul 1, 2022

In our library since:

Apr 5, 2022

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http://dl.cm-uj.krakow.pl:8080/publication/4629

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ZB-132973 Jul 1, 2022
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