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Subject:
stroke ; emotional disorders ; post-stroke depression ; C-reactive protein
Abstract:
Emotional disturbance is a common consequence of stroke. They can appear in the acute phase of the disease or in the following months. The aim of the study is to determine the frequency of emotional disorders (depression, anxiety, apathy, aggression) in patients after stroke, and to check the relationship between the occurrence of delirium in the acute phase of stroke and depression, anxiety, apathy and post-stroke aggression. The impact of post-stroke depression on changes in functioning (assessment of the level of disability) and mortality at 3 and 12 months after stroke will also be assessed. Moreover, the relationship between the concentration of c-reactive protein in the blood and the occurrence of depressive symptoms after ischemic stroke in hospitalized patients and 3 months after the stroke will be investigated. The group of another 750 people diagnosed with stroke (ischemic / haemorrhagic) or TIA, admitted to the stroke department of the Department of Neurology of the Jagiellonian University Medical College in Krakow, was included in the study. The obtained results indicate that emotional disorders are a frequent consequence of stroke. Post-stroke depression continues in more than half of patients up to 12 months after stroke, and delirium is an independent factor that increases the risk of emotional disturbance after stroke. Moreover, the occurrence of post-stroke dep ; ression significantly increases the risk of disability and death 3 and 12 months after stroke, and a higher level of C-reactive protein (CRP) is associated with the early onset of depressive symptoms after stroke.
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Level of degree:
Degree discipline:
Degree grantor:
Rada Dyscypliny Nauki medyczne
Promoter:
Klimkowicz-Mrowiec, Aleksandra