Title:

Clinical analysis of children with airway malacia

Author:

Kusak, Beata

Subject:

airway malacia ; tracheomalacia ; lung function test ; spirometry ; impulse oscillometry

Abstract:

AIM: To ascertain which respiratory symptoms are protracted in children with airway malacia (AM) at school age and how is pulmonary function (PF) of those children. METHODS: 37 children (median age 8,4 years) previously diagnosed with AM and without comorbiditis took part in this study. The study consisted of: a questionnaire establishing respiratory symptoms presence and characterization in the 1th year after AM diagnosis and currently, PF test with post-bronchodilator evaluation, exercise challenge test. RESULTS: 78% children with AM had higher respiratory infections frequency than their healthy siblings/peers in the 1th year after AM diagnosis, and in 54% it was still higher despite the school age. In about 60% of those children the course of infections was more severe than in siblings/peers and without significant improvement at school age. Postinfectious cough (in 57%) and chronic cough (in 24%) present in the 1th year after AM diagnosis did not tend to diminish with age (respectively 43% and 21%). Exercise intolerance was reported by 46%, cough on exertion by 39% children at school age. PF test outcome were: restrictive in 20%, obstructive in 13%, normal in the remainder 67%. Positive exercise challenge had 4% of children, 13% met the criteria for reversible obstruction. CONCLUSION: Children with AM have protracted respiratory symptoms at school age - more frequen ; t respiratory infections, which have more severe course and longer duration, chronic cough (1/4 children), exercise intolerance (1/2 children). In 2/3 children PF test outcomes are within the normal range and bronchial hyperresponsiveness is present in 17%.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

pulmonologia ; pediatria

Degree grantor:

Rada Dyscypliny Nauki medyczne

Promoter:

Lis, Grzegorz

Date:

2021

Date issued:

2020

Type:

Praca doktorska

Call number:

ZB-133530

Language:

pol; eng

Access rights:

nieograniczony

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