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Title: Transcatheter aortic valve implantation and minimally invasive treatment of aortic valve stenosis - long-term results, complications, prognostic factors and assessment of the quality of life

Author:

Tokarek, Tomasz

Date:

2019

Type:

Praca doktorska

Abstract:

The PhD dissertation presented an assessment of the long-term clinical outcomes and quality of life (QoL) in patients with severe aortic stenosis treated with transcatheter aortic valve implantation (TAVI) and available cardiac surgery methods (sternotomy, minithoracotomy, ministernotomy). There was no difference between groups in terms of the longest available follow-up mortality. TAVI seems to have a more favorable effect on left ventricular function and an increase in ejection fraction in comparison with the surgical methods. However, arrhythmias and conduction disturbances after the procedure were more often reported in TAVI patients. Amelioration of QoL after TAVI in comparison with surgical treatment groups was maintained up to one year after the procedure. In multivariable Cox regression analysis incomplete coronary revascularisation, estimated glomerular filtration rate, previous stroke/tran¬sient ischaemic attack and blood transfusion were identified as the only independent determinants of death in TAVI patients. Different tools for frailty evaluation were presented. Sarcopenia was evaluated with psoas muscle area and volume using computed tomography scans. Results were normalized for body surface area. This method had the highest discrimination ability among all the tested frailty tools for 12-month all-cause mortality after TAVI. The PhD dissertation confirmedutility of the frailty and QoL evaluation in patients undergoing TAVI.Transcatheter aortic valve implantation and minimally invasive treatment of aortic valve stenosis - long-term results, complications, prognostic factors and assessment of the quality of life

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Dariusz Dudek

Date issued:

2018

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:4373

Call number:

ZB-130564

Access rights:

tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

Subject and keywords:

aortic valve stenosis TAVI quality of life frailty surgical aortic valve replacement

Object collections:

Last modified:

Aug 28, 2020

In our library since:

Aug 28, 2020

Number of object content hits:

3

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4374

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Edition name Date
ZB-130564 Aug 28, 2020

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