Title:

Staphylococcus aureus infections among Polish patients of selected hospital and care institutions: epidemiology and characteristics of microorganisms

Author:

Romaniszyn, Dorota

Subject:

infections ; prevalence ; Staphylococcus aureus ; antimicrobial resistance ; genotyping

Abstract:

Hospital infections are an important cause of morbidity and mortality worldwide, especially if the etiological factor is drug-resistant microorganisms, and concems the population of the most vulnerable patients. The conducted research allowed to describe in detail the epidemiology of infections with S.aureus aetiology m southem Poland. Epidemiological analysis was carried out in vanous analytical areas, such as: type of care, population, clinical form of infection. Multicentre studies on nosocomial infections covered orthopaedic patients, newboms and long-term care residents. The PFGE typing was subjected to strains from neonatal and resident infections. Strains isolated from newboms were typed by the spa-typing method and the SCCmec chromosomal cassette was determined. As a result of the research it was found: (1) significantly higher incidence rate after knee prosthesis, while epidemiology and microbiology after the implementation of infections surveillance in hip arthroplasty did not differ from that expected; (2) in neonatology, horizontal transmission of MRSA strains; high consumption of glycopeptides in the treatment of MSSA (3) The presence of MRSA in locals is significantly associated with limited mobility: the Barthel scales can be used as a determinant of MRSA colonization in targeted screening (4) strong interpenetration of the community and ; hospital environment, which proves that drug-resistant strains are not the domain of institutional care. Among the tested neonatal isolates, the largest group was the spa tO 15 and at the same time SCCmeclV.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

mikrobiologia

Degree grantor:

Wydział Lekarski

Promoter:

Wójkowska-Mach, Jadwiga ; Chmielarczyk, Agnieszka

Date:

2018

Date issued:

2018

Type:

Praca doktorska

Call number:

ZB-130754

Language:

pol; eng

Access rights:

tylko w bibliotece

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