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infections ; prevalence ; Staphylococcus aureus ; antimicrobial resistance ; genotyping
Abstract:
Hospital infections are an important cause of morbidity and mortality worldwide, especially if the etiological factor is drug-resistant microorganisms, and concems the population of the most vulnerable patients. The conducted research allowed to describe in detail the epidemiology of infections with S.aureus aetiology m southem Poland. Epidemiological analysis was carried out in vanous analytical areas, such as: type of care, population, clinical form of infection. Multicentre studies on nosocomial infections covered orthopaedic patients, newboms and long-term care residents. The PFGE typing was subjected to strains from neonatal and resident infections. Strains isolated from newboms were typed by the spa-typing method and the SCCmec chromosomal cassette was determined. As a result of the research it was found: (1) significantly higher incidence rate after knee prosthesis, while epidemiology and microbiology after the implementation of infections surveillance in hip arthroplasty did not differ from that expected; (2) in neonatology, horizontal transmission of MRSA strains; high consumption of glycopeptides in the treatment of MSSA (3) The presence of MRSA in locals is significantly associated with limited mobility: the Barthel scales can be used as a determinant of MRSA colonization in targeted screening (4) strong interpenetration of the community and ; hospital environment, which proves that drug-resistant strains are not the domain of institutional care. Among the tested neonatal isolates, the largest group was the spa tO 15 and at the same time SCCmeclV.
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Wójkowska-Mach, Jadwiga ; Chmielarczyk, Agnieszka