Evaluation of the usefulness of plasma renin activity determination in the selection of optimal antihypertensive therapy among patients with primary hypertension according to the Laragh and Alderman concept - Digital Medical Library

Skip to main menu
Skip to search engine
Skip to content
Skip to footer

Download

This publication is protected and can be accessed only from certain IPs.

This publication is protected and can be accessed only from certain IPs.

Description
Information

Title: Evaluation of the usefulness of plasma renin activity determination in the selection of optimal antihypertensive therapy among patients with primary hypertension according to the Laragh and Alderman concept

Author:

Date:

Type:

Praca doktorska

Abstract:

The effectiveness of treatment of hypertension is low. The guidelines can be supplemented with "pathophysiological approach" to an individualized therapy.The objectives:-examination of the relationship between plasma renin activity (PRA), aldosterone and asymptomatic organ damage (AOD)-exploring the effect of antihypertensive treatment, consistent with Laragh and Alderman hypothesis, on blood pressure and AOD-evaluation of clinical and biochemical discrepancies among patients from low-renin and high-renin groups with particular reference to the values of serum lipidsOperating range: a planned prospective trial that included a total of 95-122 patients with first or second-degree hypertension.Conclusions:-the study of the effect of the renin-angiotensin-aldosterone system (RAAS) on the occurrence of AOD should include the relationship between the concentration of aldosterone and renin-PRA as the only indicator has no predictive value for the occurrence of AOD, on the other hand an aldosterone-to-renin ratio (ARR) does have it-the choice of antihypertensive drug based on PRA does not determine either the magnitude of the blood pressure reduction nor thesignificance of the AOD regression-patients with high-renin hypertension are characterized by higher serum total cholesterol and LDL-cholesterol, but the relationship between LDL-cholesterol and PRA is only in the low-renin group.

Place of publishing:

Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia

Degree grantor:

Wydział Lekarski

Promoter:

Date issued:

Identifier:

oai:dl.cm-uj.krakow.pl:4344

Call number:

Language:

Access rights:

tylko w bibliotece

Subject and keywords:

renin-angiotensin-aldosterone system plasma renin activity serum lipids arterial hypertension asymptomatic organ damage

Object collections:

Digital Medical Library > PhD thesis database

Last modified:

Jun 26, 2023

In our library since:

Jun 23, 2020

Number of object content hits:

29

Number of object content views in PDF format

0

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4345

Show description in RDF format:

Show description in OAI-PMH format:

Edition name	Date
ZB-130875	Jun 26, 2023

Objects

Similar

Evaluation of the usefulness of plasma renin activity determination in the selection of optimal antihypertensive therapy among patients with primary hypertension according to the Laragh and Alderman concept

Pizoń, Tomasz

2019

Praca doktorska

The therapeutic efficacy of the renin–angiotensin–aldosterone system inhibition on myocardial function in amurine model of dilated cardiomyopathy (Tg_x0006_q*44 mice)

Woźniak, Mirosław

2015

Praca doktorska

Influence of regular interval aerobic training on arterial stiffness and endothelial function in patients with arterial hypertension

Kameczura, Tomasz

2014

Praca doktorska

The analysis of relations between selected psychological variables and hypertension-mediated organ damage

Popiołek, Lech

2019

Praca doktorska

Features of left atrium in transthoracic echocardiography and coagulation parameters among patients with atrial fibrillation in comparison to healthy persons and hypertensives

Kocowska, Maryla

2016

Praca doktorska

Evaluation of selected indicators of the coagulation system and fibrinolysis and exercise capacity of patiensts with idiopathic atrerial and chronic thromboembolic pulmonary hypertension

Widlińska, Barbara

2019

Praca doktorska

Influence of genetic polymorphisms of angiotensinogen, angiotensinconverting enzyme and type 1 angiotensin II receptor on large artery stiffness parameters

Cwynar, Marcin

2006

Praca doktorska

Etiopathogenesis of hypertension

Dzieża-Grudnik, Anna

2024

Praca doktorska

More

Citation style:

Contact details

Address

Medical Library
Medyczna 7
30-688 Krakow

Phone

12 658 72 56
517 385 669

E-Mail

Collecting and Elaboration Department
cyfrowabm@cm-uj.krakow.pl

Visit us!

https://bm.cm.uj.edu.pl/en/main-page/

This page uses 'cookies'. More information