Role of new markers of nephropathy associated with diabetes mellitus type 2 - Digital Medical Library

Skip to main menu
Skip to search engine
Skip to content
Skip to footer

Role of new markers of nephropathy associated with diabetes mellitus type 2

Download

Description
Information

Title: Role of new markers of nephropathy associated with diabetes mellitus type 2

Author:

Żyłka, Agnieszka

Date:

Type:

Praca doktorska

Abstract:

The doctoral thesis is based on a monothematic series of articles, which consists of a total of 4 works, including 3 original and 1 review work. The aim of this dissertation was to search for new markers of diabetic kidney disease (DKD) allowing for early diagnosis prior to the development of irreversible changes at the level of nephrons. In the course of the conducted research, in the group of diabetic patients, the biomarkers of both renal tubular damage: NGAL in urine and blood, KIM-1 in urine, uromodulin in blood serum and urine, and glomerular damage: albuminuria, transferrin and IgG in urine and CysC in blood serum, were examined. Diagnostic utility of the examined biomarkers in prediction of early stages of tubulopathy development associated with diabetes and renal glomerular damage before albuminuria was demonstrated, thus creating the possibility of using their index as new diagnostic tools aimed at early diagnosis of kidney damage in diabetes in its preclinical stage. The currently used nephroprotective treatment primarily affects renal glomerules, while the effect on the nephron tubules remains unclear. The presented finding forecasts a change in the diagnostics and treatment of patients at early-stage of DKD.

Place of publishing:

Level of degree:

2 - studia doktoranckie

Degree discipline:

Degree grantor:

Wydział Lekarski

Promoter:

Kuśnierz-Cabala, Beata ; Gala-Błądzińska, Agnieszka

Date issued:

Identifier:

oai:dl.cm-uj.krakow.pl:4343

Call number:

Language:

Access rights:

Subject and keywords:

diabetes mellitus type2 biomarkers albuminuria diabetic kidney disease neutrophil gelatinase-associated lipocalin

Object collections:

Digital Medical Library > PhD thesis database

Last modified:

Jun 26, 2023

In our library since:

Jun 23, 2020

Number of object content hits:

250

Number of object content views in PDF format

225

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4344

Show description in RDF format:

Show description in OAI-PMH format:

Edition name	Date
ZB-130899	Jun 26, 2023

Objects

Similar

Role of new markers of nephropathy associated with diabetes mellitus type 2

Żyłka, Agnieszka

2019

Praca doktorska

The role of clinical and genetical risk factors in pathogenesis of diabetic retinopathy in patients with type 2 diabetes

Cyganek, Katarzyna

2007

Praca doktorska

Novel factors modifying properties of fibrin and efficiency of fibrinolysis in patients with type 2 diabetes mellitus

Bryk-Wiązania, Agata

2021

Praca doktorska

Insulin resistance candidate gene polymorphisms and predisposition to Type 2 diabetes mellitus

Wanic, Krzysztof

2005

Praca doktorska

Surgical treatment for morbid obesity in patients with type 2 diabetes mellitus

Wysocki, Michał

2021

Praca doktorska

Influence of growth and inflammation factor of the development of nephropathy and vascular compilations in diabetic type 2 patients

Miarka, Przemysław

2009

Praca doktorska

The concentration of osteopontin in the patients' blood serumwith clinically and histologically confirmed endometriosis

Figuła, Joanna

2019

Praca doktorska

Urinary concentration of biomarkers of occupational exposure to polycyclic aromatic hydrocarbons, and its relationship to chosen genetic mutations

Zając, Joanna

2017

Praca doktorska

More

Citation style:

Contact details

Address

Medical Library
Medyczna 7
30-688 Krakow

Phone

12 658 72 56
517 385 669

E-Mail

Collecting and Elaboration Department
cyfrowabm@cm-uj.krakow.pl

Visit us!

https://bm.cm.uj.edu.pl/en/main-page/

This page uses 'cookies'. More information