Title:

Disorders of sexuality and selected metabolic disorders as consequences of systemic treatment in women with breast cancer

Author:

Streb, Joanna

Subject:

vitamin D ; breast cancer ; sexuality

Abstract:

The work was aimed at determining the indications for sexological consultations in women after surgical treatment of breast cancer, taking into account the differences resulting from the nature of the operation (radical procedure and Breast Conserving Treatment), as well as medical and demographic characteristics of the women surveyed. An attempt was made to answer the questions about the existence of differences in the perception of one's carnality between healthy women and those treated for breast cancer, and whether these differences are influenced by the type of treatment and pre-operative parameters. Women who were physically active in whom the surgery was related to the right breast (on the dominating side), obtained a lower score on the "sexual functioning" QLQ-BR-23 scale than women after the left breast surgery. There was a statistically significant correlation between the initial state of Zubrod scale and the scale: desire, vaginal lubrication and satisfaction in the PL-FSFI questionnaire. We therefore pointed to the effectiveness of using the simple Zubord scale in predicting the risk of a drop in the quality of life and the occurrence of sexual dysfunction in women after mastectomy. Patients after breast surgery, regardless of the scope of surgery, showed significantly lower scores in two categories: body acceptance and intimacy.Another analyzed problem was the rela ; tionship between breast cancer treatment and vitamin D concentration. The concentration of 25 (OH) D was lower in breast cancer patients than in healthy women, regardless of their menopausal status. The lowest plasma concentrations of vitamin 25 (OH) D occurred in patients with ER and PR positive tumors. In addition, the new (original) observation was that a significant reduction in 25 (OH) D was observed during chemotherapy. This observation can have significant clinical implications, indicating on the need for vitamin D supplementation in women treated for breast cancer during and after treatment.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

ginekologia

Degree grantor:

Wydział Lekarski

Promoter:

Jach, Robert

Date:

2018

Date issued:

2018

Type:

Praca doktorska

Call number:

ZB-130603

Language:

pol; eng

Access rights:

nieograniczony

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