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The assessment of laboratory markers of the affective disorders

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Title: The assessment of laboratory markers of the affective disorders

Author:

Styczeń, Krzysztof

Date:

2018

Type:

Praca doktorska

Abstract:

The aim of the presented study was the assessment of zinc and copper concentrations among patients with MDD and healthy volunteers and additionally comparison of those concentrations between patients with MDD and BD. 110 patients with the diagnose of BD and 114 with MDD were qualified to this case-control study. To assess the levels of microelements the flame atomic absorption spectrometry in zinc samples was used and the electrothermal atomic absorption spectrometry for copper samples was used.The zinc level in MDD patients in depression was significantly lower than in healthy volunteers. Between MDD patients in remission and healthy volunteers no differences were obtained. Copper levels analysis have not shown significant differences between MDD patients (in remission or depression) and healthy volunteers nor among majority of analyzed correlations. The levels of copper and zinc in BD and MDD patients (both in remission and depression) did not differ. The zinc concentration has some features of state marker with no features of trait marker of MDD. Copper level does not have any features of a state or trait marker of MDD. The lack of differences in zinc and copper concentrations between patients with bipolar disorder and major depressive disorder might indicate that those disorders have similar etiology.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

psychiatria ; biochemia

Degree grantor:

Wydział Lekarski

Promoter:

Dudek, Dominika

Date issued:

2018

Identifier:

oai:dl.cm-uj.krakow.pl:4301

Call number:

ZB-129266

Language:

pol; eng

Access rights:

nieograniczony

Subject and keywords:

biomarkers copper affective disorders zinc

Object collections:

Last modified:

Jun 26, 2023

In our library since:

Jul 9, 2019

Number of object content hits:

236

Number of object content views in PDF format

217

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4302

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Edition name Date
ZB-129266 Jun 26, 2023

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