Advanced search ?

Object

Evaluation of fatty acids profile in patients after heart or renal transplantation

Download

Title: Evaluation of fatty acids profile in patients after heart or renal transplantation

Author:

Wilusz, Malgorzata

Date:

2018

Type:

Praca doktorska

Abstract:

The aim of the study was to assess the fatty acids profile in phospholipid fractions, in patients after heart or kidney transplantation, depending on: the type of immunosuppressive drug, transplanted organ, metabolic disorders and kidney function. The doctoral dissertation consists of four scientific publications. The review article, contains information about the type and role of fatty acids. The study included: 23 heart transplant patients (9 treated with cyclosporine (CsA), 14 treated with tacrolimus (Tac)) and 65 kidney transplant recipients (24 treated with CsA, 41 treated with Tac). The study also included 25 healthy, non-transplanted individuals who set up control groups. The concentration of fatty acids was determined by gas chromatography. The obtained results confirm that the fatty acid profile of patients after transplantation is different than in healthy people. In addition, in patients after heart transplantation, the fatty acid profile depends on the type of immunosuppressant used. In kidney transplant patients, treated with Tac, with hyperlipidaemia, the metabolism of saturated fatty acids and n-6 acids is different than in patients without metabolic disorders. In turn, the analysis of the correlation between fatty acid concentration and eGFR, showed that fatty acids are essential for normal kidney function, and their role depends on the type of fatty acid.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

transplantologia ; biochemia

Degree grantor:

Wydział Lekarski

Promoter:

Sztefko, Krystyna

Date issued:

2018

Identifier:

oai:dl.cm-uj.krakow.pl:4294

Call number:

ZB-129172

Language:

pol; eng

Access rights:

nieograniczony

Subject and keywords:

tacrolimus metabolic disorders cyclosporin A fatty acids transplantation

Object collections:

Last modified:

Jun 26, 2023

In our library since:

May 30, 2019

Number of object content hits:

120

Number of object content views in PDF format

122

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4295

Show description in RDF format:

RDF

Show description in OAI-PMH format:

OAI-PMH

Edition name Date
ZB-129172 Jun 26, 2023

Objects

Similar

Evaluation of fatty acids profile in patients after heart or renal transplantation

Wilusz, Malgorzata

2018
Praca doktorska

The influence of metabolic stress factors and quercetin on mitochondrial function ofpreadipocytes

Dziewońska, Agnieszka

2013
Praca doktorska

The influence of a diet on change of genes’ expression for elongases and desaturases of fatty acids in rats

Drąg, Jagoda

2011
Praca doktorska

The influence of the selected fatty acids on expression gene of aromatase in progenital cells of human adipose tissue

Dudek, Wojciech

2008
Praca doktorska

The aim of the study was to assess the influence of a single bout of maximal exercise in water at 4°C on blood rheological properties and the composition of fatty acids in erythrocyte membranes of laboratory rats

Teległów, Aneta

2010
Praca doktorska

The biochemical parameters of postprandial lipemia in patient with metabolic syndrome

Wnęk, Dominika

2016
Praca doktorska

The effect of omega-3 polyunsaturated fatty acids on coagulation, platelets activation, endothelial function and course of coronary artery disease in patients with high cardiovascular risk

Siniarski, Aleksander

2021
Praca doktorska

Pleiotropic effects of hipolipemic drugs, anti-3-Hydroxy-3-Methylglutaryl Coenzyme A (statins) and omega-3 polyunsaturatedfatty acids in coronary artery disease

Mostowik, Magdalena

2016
Praca doktorska
More
×

Citation

Citation style:

Contact details

Address

Medical Library
Medyczna 7
30-688 Krakow

Phone

12 658 72 56
517 385 669

E-Mail

Collecting and Elaboration Department
cyfrowabm@cm-uj.krakow.pl

Visit us!

This page uses 'cookies'. More information