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Title: Assessment of left ventricle function in obese and overweight women, without concomitant cardiovascular diseases

Author:

Golińska-Grzybała, Karolina

Date:

2018

Type:

Praca doktorska

Abstract:

Purpose: The aim of this study was to evaluate the potential relationship between the left ventricle (LV) function in overweight and obese pregnant women and parameters of blood flow in uterine arteries.Methods: We conducted a prospective cohort study, which included consecutive 83 women with singleton pregnancy. They were divided into 3 groups (gr): gr. 1 - 32 (BMI ≤ 24.9 kg/m2), gr. 2 - 28 (BMI 25.0-29.9 kg/m2) and gr. 3 - 23 (BMI ≥ 30 kg/m2). During pregnancy blood pressure, echocardiography and the assessment of blood flow in uterine arteries - pulsatility index (PI) and resistance index (RI) were assessed at two visits (V): V1 between 10 and 15 weeks and V2 between 25 and 30 weeks of gestation.Results: In gr. 3 in comparison to group 1 and 2, higher systolic, diastolic, and mean arterial pressure, as well as systemic vascular resistance (SVR) were observed during V2. Traditional parameters of LV systolic function like ejection fraction and fractional shortening were slightly decreased in obese women. Although cardiac output (CO) was similar in all groups during both visits, cardiac index (CI) was significantly lower during V1 and V2 in gr.3. What is more, a negative correlation between RI measured at V2 and CI at V1 (r=-0.345, p=0.004) was found.Conclusions: Subclinical left ventricle dysfunction in obese and overweight women may contribute to placental hypoperfusion and higher resistance in uterine arteries. This may lead in some women to preeclampsia.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia ; położnictwo

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Ewa Konduracka

Date issued:

2018

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:4246

Call number:

ZB-128622

ControlNumberVIRTUA:

click here to follow the link

Language:

pol

Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

Subject and keywords:

left ventricle echocardiography pregnancy obesity

Object collections:

Last modified:

May 24, 2021

In our library since:

Aug 24, 2018

Number of object content hits:

998

Number of object content views in PDF format

990

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4247

Show description in RDF format:

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Show description in OAI-PMH format:

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Edition name Date
ZB-128622 May 24, 2021

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