Aim of the study: Based on the assumption that the risk of urethral invasion is low at patients with organ-confined prostate cancer, The aims of this prospective study were as follows: ● Assessment of the feasibility of dissection of the prostatic urethra from the prostatic tissue ● Assessment of the cancer invasion in the urethra● Evaluation of the risk factors associated with the cancer invasion into the urethra Conclusions: 1. In a group of 88 patients, the prostatic urethra was effectively removed ex vivo from all of the postoperative specimens. It was found that the dissection of this part of the urethra without leaving the remnants of the prostate gland is not technically feasible. 2. In 11 cases (12,5%), cancer cells were detected within the dissected prostatic urethra. 3. There was correlation between the invasion of the prostatic urethra and the following preoperative clinical characteristics: higher PSA level, greater local extent of the disease assessed clinically (cT) 4. There was correlation between the invasion of the prostatic urethra and the following pathologic parameters: greater local extent of the disease after pathologic staging (pT),invasion of perineural tissue within the tumour 5. The results of this study provide foundation for further research involving modification of laparoscopic radical prostatectomy technique, which is aimed prostatic urethra prese ; rvation in order to reduce the rate of the postoperative urinary incontinence.
Chłosta, Piotr ; Gołąbek, Tomasz
Jun 26, 2023
May 10, 2018
459
122
http://dl.cm-uj.krakow.pl:8080/publication/4244
Edition name | Date |
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ZB-128096 | Jun 26, 2023 |
Jaskulski, Jarosław
Ostrowski, Ireneusz
Hetnał, Marcin
Stangel-Wójcikiewicz, Klaudia