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Title: Signification of the dynamics changes of ST-segment in ECG in the assessment of myocardial reperfusion effectiveness in acute myocardial infarction with persistent ST-segment elevation patients with co-existing hyperglycaemia

Author:

Andres, Marek

Date:

2016

Type:

Praca doktorska

Abstract:

The aim of this study was to evaluate the dynamics of ST-segment changes in ECG in STEMI patients with co-existing hyperglycaemia compared to those with normoglycaemia treated with percutaneous coronary intervention, as well as to determine this parameter in the assessment of reperfusion effectiveness. Additionally, thestudy evaluated the likelihood of developing diabetes in the long-term follow-up of patients with the impaired glucose metabolism diagnosed during hospitalization due to STEMI. In the first stage of the study the population of patients was divided into groups based on reactive hyperglycaemia or HbA1c concentration: a group with Glc ≥ 7.8 mmol/L, n = 46, a group with Glc < 7.8 mmol/L, n = 46, a group with HbA1c levels <6.5%, n = 71and a group with HbA1c levels (≥6.5%, n = 21). In the second stage of the study the analysis covered three patient subgroups divided according to the following scheme: subgroup A = Glc < 7.8 mmol/L and HbA1c ≤ 6.5% (n = 37), subgroup B = Glc ≥ 7.8 mmol/L and HbA1c ≤ 6.5% (n = 27), subgroup C = Glc ≥ 7.8 mmol/L and HbA1c > 6.5% (n = 20). Myocardial reperfusion after primary angioplasty in acute myocardial infarction, which is determined by the degree of resolution of ST elevation in ECG, depends on the state of the glucose metabolism. The dynamics of changes in the ST-segment in ECG, taken immediately after pCI, is lower in patients with reactive hyperglycaemia. The group of patients with disturbed glucose metabolism and impaired reperfusion had the worse clinical course. The likelihood of developing diabetes in a long-term follow-up was greater in the subgroup C.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia ; endokrynologia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Krzysztof Żmudka

Date issued:

2016

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:4174

Call number:

ZB-126051

ControlNumberVIRTUA:

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Language:

pol

Access rights:

tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

Subject and keywords:

reactive hyperglycaemia glycated haemoglobin acute myocardial infarction with persistent ST-segment elevation resolution of ST-segment elevation in ECG percutaneous coronary revascularization

Object collections:

Last modified:

May 24, 2021

In our library since:

Jun 27, 2017

Number of object content hits:

13

Number of object content views in PDF format

12

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4175

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Edition name Date
ZB-126051 May 24, 2021

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