This publication is protected and can be accessed only from certain IPs.
This publication is protected and can be accessed only from certain IPs.

Title: The assessment of anthracycline-induced cardiotoxicity inlymphoma patients on the basis of own material


The aim of this study was to assess of anthracycline induced cardiotoxicity in lymphoma patients. The data for32 patients was analyzed prospectively, and 62 patients underwent retrospective analysis. A 10% reduction in the ejection fraction was found for 13 out of 29 patients from prospective group and for 20 out of 62 patients from the retrospective group. Serious cardiac events were noticed in10 out of 29 patients analyzed prospectively and 13 out of 62 patients analyzed retrospectively. Significantly higher incidence of mortality independently of the direct cause was found in patients with an ejection fraction of 55% prior to chemotherapy, and an early reduction in ejection fraction after 2-4 administrations of doxorubicin to a value of 55% compared to patients with an ejection fraction > 55%.The left ventricle relaxation was abnormal for 11 out of 31 patients in the prospective group and for 9 out of 39 patients in the retrospective group. The diastolic dysfunction was more frequent in the patients with serum troponin T concentration > 0.025ng/ml and in the patients with high serum NT-proBNP concentration after the first doxorubicin treatment. Decreased PFR during the exercise test in GSPECT assessment was detected in the prospectively analyzed group of patients after chemotherapy. Decreased PFR was seen in 9 out of 12 patients when GSPECT was investigated.

Place of publishing:


Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia ; onkologia

Degree grantor:

Wydział Lekarski


Pluta, Andrzej

Date issued:




Call number:




Access rights:

tylko w bibliotece

Object collections:

Last modified:

Mar 15, 2023

In our library since:

Sep 22, 2016

Number of object content hits:


Number of object content views in PDF format


All available object's versions:


Show description in RDF format:


Show description in OAI-PMH format:


Edition name Date
ZB-125263 Mar 15, 2023


Citation style:

This page uses 'cookies'. More information