Title:

Acute kidney injury in course Hantavirus infection – analysis diseases from the Podkarpacki region

Author:

Bentkowski, Wacław

Subject:

Puumala virus ; Dobrava virus ; haemorrhagic fever with renal syndrome ; acute kidney injury (AKI) ; Podkarpacki region

Abstract:

Viral haemorrhagic fevers are zoonoses infections. They differ in clinical course, ways of infection, disease symptoms, and their common feature is hemorrhages to the internal organs and the skin. In Europe, there are mainly two Hantvirus serotypes: Puumala serotype which causes a mild form of haemorrhagic fever called epidemic nephropathy and Dobrava serotype which causes hemorrhagic fever with renal syndrome (HFRS).In the Podkarpacki region during 2007-2012 Hantavirus infection disease was found in 38 patients; serotype Dobrava 50% and serotype Puumala 50%. The aim of the study was to assess what percentage of Hantavirus-infected patients have kidney damage, what were the predominant symptoms from the urinary tract, what was the duration of acute kidney injury (AKI), and the evaluation of the consequences of Hantavirus infection. Dominant signs of Hantavirus infection are flu-like symptoms with a high temperature, discomfort on the part of the digestive system, volemia disorders, low levels of platelets, elevated serum creatinine, urea nitrogen and CRP. AKI occurred in 75% of patients and lasted about of 9 days. 5 patients requiring hemodialysis. A complete remission of renal function was observed in 68% of patients and partial in 32%. AKI of Hantavirus infection does not result in permanent damage of the kidney.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

nefrologia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Władysław Sułowicz

Date:

2015

Date issued:

2015

Type:

Praca doktorska

Format:

application/pdf

Call number:

ZB-124226

ControlNumberVIRTUA:

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Language:

pol

Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum