Obiekt
Tytuł: Effects of cardiac resynchronisation therapy on the autonomic nervous system function, sleep disorders, and vascular stiffness
Abstract:
The aim of this study was simultaneous evaluation of CRT effects on the autonomic nervous system function, sleep disorders, arterial stiffness, depression level, as well as an assessment of their interactions, together with an analysis of a clinical response of all these parameters to CRT. The study covered 55 people with chronic heart failure stable for at least last 3 months, in the NYHA class III-IV despite optimal pharmacotherapy, with sinus rhythm present during the examination, a left ventricular ejection fraction (LVEF) ≤ 35%, wide QRS complexes ≥ 120 ms. In the whole group a statistically significant increase in the arterial baroreflex sensitivity (BRS) when lying and return their ability to modulate in response to orthostatic stimulus were observed. The values of apnea-hypopnea index, as well as central and mixed apnea indexes were statistically significantly reduced. A shift in dominance from central to obstructive sleep apnea was also observed. Beneficial effects of CRT were noted for subjective sleep parameters and depression level. Significant changes weren’t demonstrated for arterial stiffness. Negative correlations between changes of polysomnographic parameters, subjective sleep parameters and depression intensity with changes of BRS and LVEF were affirmed. The clinical improvement defined as an improvement by at least one NYHA class was connected with an improve ; ment in polysomnographic parameters and subjective parameters evaluating sleep quality, daytime sleepiness and depression level, as well as with an improvement in the autonomic nervous system function and arterial stiffness.
Place of publishing:
Level of degree:
Degree discipline:
Degree grantor:
Promoter:
Date issued:
Identifier:
Call number:
Language:
Access rights:
Kolekcje, do których przypisany jest obiekt:
Data ostatniej modyfikacji:
Mar 16, 2023
Data dodania obiektu:
Feb 1, 2016
Liczba wyświetleń treści obiektu:
13
Liczba wyświetleń treści obiektu w formacie PDF
0
Wszystkie dostępne wersje tego obiektu:
http://dl.cm-uj.krakow.pl:8080/publication/4038
Wyświetl opis w formacie RDF:
Wyświetl opis w formacie OAI-PMH:
| Nazwa wydania | Data |
|---|---|
| ZB-123739 | Mar 16, 2023 |
Obiekty
Podobne
Przybyła, Anna
Wiliński, Jerzy
Kusiak, Aleksander
Sondej, Tomasz
Kloch-Badełek, Małgorzata
Kisiel, Roksana
