Diagnostic ability of serum UM in identifying individual stages of CKD - Digital Medical Library

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Title: Diagnostic ability of serum UM in identifying individual stages of CKD

Author:

Fugiel, Andrzej

Date:

Type:

Praca doktorska

Abstract:

The aim of this study was to confirm the existence of a link between the concentration in the blood serum of UM and the prevalence of CKD. The study group included adult patients with CKD stage I-N. The association between serum concentrations of UM, and serum creatinine, cystatin C, and the values of all available data calculated from eGFR formulas was analyzed. The relationship between the serum concentration of UM and biochemical markers of inflammation, calcium-phosphate, malnutrition, peripheral blood counts and NTproBNP was also analyzed. Serum UM decreases with progressive loss of kidney function; this is significantly and negatively correlated with the concentration of creatinine and cystatin C and positively correlated with all applied variables in the analysis models for estimating GFR. The analysis showed that the relationship between UM concentration and eGFR remains independent of key demographics. Based on the results of research and statistical analysis it is proposed to recognize the serum concentration of UM as a new biomarker for assessing renal function.

Place of publishing:

Level of degree:

2 - studia doktoranckie

Degree discipline:

Degree grantor:

Wydział Lekarski

Promoter:

Kuźniewski, Marek

Date issued:

Identifier:

oai:dl.cm-uj.krakow.pl:4037

Call number:

Language:

Access rights:

Subject and keywords:

laboratory diagnosis of CKD uromodulin stages of CKD biomarkers of renal function

Object collections:

Digital Medical Library > PhD thesis database

Last modified:

Jun 26, 2023

In our library since:

Feb 1, 2016

Number of object content hits:

672

Number of object content views in PDF format

110

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/4037

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Edition name	Date
ZB-123664	Jun 26, 2023

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