Title:

Prediction of infarct size and post-infarct left ventricular remodeling in patients with ST-elevation myocardial infarction treated with percutaneous coronary angioplasty

Author:

Lech, Piotr

Subject:

myocardial infarction ; percutaneous coronary interventions ; infarct size

Abstract:

Background. Infarct size is an important factor affecting left ventricular contractility, function, in-hospital and long-term prognosis. At present, there is no method available that would allow to assess post-infarction necrotic zone size in an easy manner.Aim. To create a mathematical formula which would allow to estimate infarct size and post-infarct remodelling of left ventricle.Material and methods. 120 patients with first, acute ST-elevation myocardial infarction undergoing primary coronary angioplasty were included in the study. Each of these patients had routine laboratory, angiographic and clinical parameters measured, and serial assessments of necrotic marker levels and ECG were performed. Based on magnetic resonance results, infarct size, ejection fraction and remodelling parameters were obtained.Results. Based on obtained data, a linear regression formula was created that enables to estimate infarct zone and post-infarction left ventricular ejection fraction. Unfortunately, attempts to create a model to estimate post-infarction remodelling were not successful.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Krzysztof Żmudka

Date:

2015

Date issued:

2014

Type:

Praca doktorska

Format:

application/pdf

Call number:

ZB-122887

ControlNumberVIRTUA:

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Language:

pol

Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

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