Urinary neutrophil gelatinase associated lipocalin (NGAL) as the early biomarker of diabetic kidney disease in the course of diabetes mellitus type 2 - Digital Medical Library

Skip to main menu
Skip to search engine
Skip to content
Skip to footer

Download

Description
Information

Title: Urinary neutrophil gelatinase associated lipocalin (NGAL) as the early biomarker of diabetic kidney disease in the course of diabetes mellitus type 2

Author:

Gala-Błądzińska, Agnieszka

Date:

Type:

Praca doktorska

Abstract:

The study evaluates the role of measurements of neutrophil gelatinase-associated lipocalin (NGAL), and albumine and NGAL to creatine (UACR, uNGAL/uCr) markers obtained in the morning urine sample in early diagnosis of diabetic kidney disease (DKD).The study comprises 55 Type 2 diabetic patients (DM t2) aged 18 and over. The data were compared against a group of 22 non-diabetic individuals. Statistically, uNGAL/uCr is much higher in the DM t2 group. uNGAL/uCr and UACR is significantly higher in women and patients with DM t2 and cardiovascular complications. In the DM t2 group, the patient’s age and HbA1c are independent predictive factors for the concentration of uNGAL and uNGAL/uCr. uNGAL and uNGAL/uCr are clinically useful, early, changing dynamically in time, non-invasive DKD indicators, specific for renal tubule damage. The RAA blockade and statin treatment have no influence on the functioning of kidney tubules in DM t2 assessed by uNGAL and uNGAL/uCr.Leucocyturia limits the utility of uNGAL in DKD diagnosis.

Place of publishing:

Level of degree:

2 - studia doktoranckie

Degree discipline:

endokrynologia ; nefrologia

Degree grantor:

Wydział Lekarski

Promoter:

Kuźniewski, Marek

Date issued:

Identifier:

oai:dl.cm-uj.krakow.pl:3984

Call number:

Language:

Access rights:

Subject and keywords:

CChN DM t2 NGAL

Object collections:

Digital Medical Library > PhD thesis database

Last modified:

Jun 26, 2023

In our library since:

May 12, 2015

Number of object content hits:

682

Number of object content views in PDF format

98

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/3984

Show description in RDF format:

Show description in OAI-PMH format:

Edition name	Date
ZB-122584	Jun 26, 2023

Objects

Similar

Urinary neutrophil gelatinase associated lipocalin (NGAL) as the early biomarker of diabetic kidney disease in the course of diabetes mellitus type 2

Gala-Błądzińska, Agnieszka

2015

Praca doktorska

Chronic kidney disease (CKD) in data of the Emergency Department of the Regional Hospital in Kielce and the Outpatient Nephrology Clinic of the University Hospital in Cracow

Wróbel, Paweł

2018

Praca doktorska

Evaluation of the diagnostic and prognostic accuracy of angiopoietin-2 (Ang-2) and neutrophil gelatinase-associated lipocalin (NGAL) as markers of the severity and complications of acute pancreatitis in the early phase of the disease

Sporek, Mateusz

2016

Praca doktorska

The analysis of diagnostic utility of selected protein markers in laboratory monitoring of patients with functioning renal transplant

Kielar, Małgorzata

2022

Praca doktorska

Influence of growth and inflammation factor of the development of nephropathy and vascular compilations in diabetic type 2 patients

Miarka, Przemysław

2009

Praca doktorska

Role of new markers of nephropathy associated with diabetes mellitus type 2

Żyłka, Agnieszka

2019

Praca doktorska

More

Citation style:

Contact details

Address

Medical Library
Medyczna 7
30-688 Krakow

Phone

12 658 72 56
517 385 669

E-Mail

Collecting and Elaboration Department
cyfrowabm@cm-uj.krakow.pl

Visit us!

https://bm.cm.uj.edu.pl/en/main-page/

This page uses 'cookies'. More information