Title:

Evaluation of adhesion of Streptococcus mutans to orthodontic materials and comparison of antiseptic properties of chlorhexidine and taurine haloamines against selected microorganisms of orthodontic biofilm

Author:

Pasich, Ewa

Subject:

orthodontic appliances ; chlorhexidine ; taurine ; biofilm

Abstract:

Uncontrolled growth of bacteria of dental plaque generates formation of oral biofilm. It may induce local inflammation with further development of dental carries and periodontal diseases. Orthodontic appliances facilitate bacteria adhesion and accelerate oral biofilm formation. It remains controversial which orthodontic material has favorable surface characteristics for bacteria adhesion. Chlorhexidine (CHX) is the common antiseptic (anti-biofilm agent) in dentistry. However, other new antiseptics are still tested. Aims: Evaluation of adhesive properties of S. mutans and C. albicans to the selected orthodontic materials (acryl, chromo-nickel steel, chromo-cobalt steel and composite plates). Comparison of anti-microbial effectiveness of CHX, taurine haloamines (TauBr, TauCl) against planktonic and biofilm form of the selected microorganisms. Moreover, their anti-inflammatory and anti-oxidant properties have been compared.• Composite plates showed the highest adhesion of S. mutans and C. albicans. The presence of C. albicans promoted the formation of S. mutans biofilm.• CHX showed the strongest antimicrobial activity against all tested pathogens. • TauBr markedly inhibited the growth of planktonic S. mutans, with the moderate effect on C. albicans. TauBr killed bacteria in biofilm, but after the long-time incubation. • In contrast to superior anti-biofilm properties of CHX compared to TauBr, the latter showed the stronger anti-inflammatory properties. TauBr, due to its properties, may be used in combination with CHX.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

stomatologia ; immunologia ; mikrobiologia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Janusz Marcinkiewicz

Date:

2015

Date issued:

2014

Type:

Praca doktorska

Format:

application/pdf

Call number:

ZB-122349

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Language:

pol

Access rights:

tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

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