Advanced search ?

Object

Download

Title: Endothelial function in atrial fibrillation

Author:

Rewiuk, Krzysztof

Date:

2014

Type:

Praca doktorska

Abstract:

Introduction: The risk of thromboembolic events in atrial fibrillation (AF) is partially independent of the arrhythmia itself. Endothelial dysfunction could be a pathogenic factor of this phenomenon.Method: The study included 60 patients with recent onset AF (up to 48h), candidates for pharmacological cardioversion. Patients underwent bFMD examination and markers associated with endothelial function (vWF, sE-selectin, ADMA, SDMA, OPG, PTX3, TRAIL, hsCRP) were determined. Patients were re-examined after 7-10 days, using the same assay.Results: The biochemical markers indicated vascular endothelial dysfunction and were partially associated with the presence of co-morbidities. The persistance of atrial fibrillation was associated with a significant decrease in the bFMD while cardioversion to sinus rhythm was not connected with improvement of this parameter. Test markers were not predictors of sinus rhythm return, but allow to predict the presence of the indications for anticoagulation.Conclusions: Patients with acute onset AF are characterized by endothelial dysfunction. The longer duration of arrhythmia leading to further deterioration of endothelial function while the successful cardioversion does not bring the improvement in the short term. The parameters of endothelial function may help to identification of patients with indications for chronic anticoagulation.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia

Degree grantor:

Wydział Lekarski

Promoter:

Grodzicki, Tomasz

Date issued:

2013

Identifier:

oai:dl.cm-uj.krakow.pl:3896

Call number:

ZB-120486

Language:

pol

Access rights:

nieograniczony

Subject and keywords:

atrial fibrillation FMD endothelium

Object collections:

Last modified:

Jun 26, 2023

In our library since:

May 15, 2014

Number of object content hits:

513

Number of object content views in PDF format

229

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/3896

Show description in RDF format:

RDF

Show description in OAI-PMH format:

OAI-PMH

Edition name Date
ZB-120486 Jun 26, 2023

Objects

Similar

Endothelial function in atrial fibrillation

Rewiuk, Krzysztof

2014
Praca doktorska

The role of endothelium and disturbances of blood flowautoregulationin the pathogenesis of reflex syncope

Wnuk, Mateusz

2012
Praca doktorska

Endothelial dysfunction in systemie connective tissue diseases

Pacholczak-Madej, Renata

2019
Praca doktorska

Relationship between selected polymorphisms of gene encoding p22phox subunit of the NADPH oxidase and endothelial function in patients with type 2 diabetes

Osmenda, Grzegorz

2007
Praca doktorska

Effect of fenofibrate therapy on brachial artery diastolic response, and plasma N1-methylnicotinamide, and homocysteine concentrations in the subjects with dyslipidemia

Kotuła-Horowitz, Katarzyna

2020
Praca doktorska

Cryoballoon pulmonary vein isolation - predictors oflongterm effectiveness and periprocedural complications

Kiełbasa, Grzegorz Stanisław

2022
Praca doktorska

The analysis of the anticoagulant effect in pactients with non-valvular atrial fibrillation during oral anticoagulation

Lenart-Migdalska, Aleksandra

2022
Praca doktorska

Features of left atrium in transthoracic echocardiography and coagulation parameters among patients with atrial fibrillation in comparison to healthy persons and hypertensives

Kocowska, Maryla

2016
Praca doktorska
More
×

Citation

Citation style:

Contact details

Address

Medical Library
Medyczna 7
30-688 Krakow

Phone

12 658 72 56
517 385 669

E-Mail

Collecting and Elaboration Department
cyfrowabm@cm-uj.krakow.pl

Visit us!

This page uses 'cookies'. More information