STEMI is a clinical problem in terms of selecting the optimal method of treatment and periprocedural proceedings. Thrombectomy as well as inh. gp 2b/3a are the methods for improving coronary perfusion and reducing myocardial injury. Previous studies, incl. 16 RCT, are different in terms of impact on LV function and late outcomes. The purpose of study is the evaluation of the impact of different pPCI strategies on the results of selected LV parameters and confirmation that a specific periprocedural intervention has an influence on long-term outcome. The prospective, randomized study involved 60 STEMI patients with ischemia lasting less than <12 h. Demographic factors as well as risk factors, ST resolution, size of enzymatic damage and angiographic parameters (TIMI,TMPG) were assessed. Transthoracal echocardiography and magnetic resonance imaging was performed at two time points: 3-5 days and at 6 m. after STEMI. Clinical observation involved the hospital period, 6 m. and 71±4 m. follow-up . Direct stenting was significantly more frequent in the aspiration groups. Thromboaspiration in STEMI was associated with comparable angiographic results and intermediate myocardial perfusion markers compared to conventional PCI with abciximab. After thromboaspiration, based on CMR, there was a significant reduction of irreversible components (MVO) in MI zone as well as lower LV remodeling aft ; er 6m. The different periprocedural proceeding didn’t affect the long outcomes, although the trend towards less frequent composite endpoint because of the lower number of cardiac hospitalizations in the conventionally treated group.
Mar 20, 2023
Jan 9, 2014
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http://dl.cm-uj.krakow.pl:8080/publication/3649
Edition name | Date |
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ZB-119476 | Mar 20, 2023 |
Zajdel, Wojciech J.
Węgiel, Michał Jan
Durak, Monika
Grzymała-Lubańska, Joanna
Dziewięcka, Ewa Maria
Wojdyła, Roman