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Title: Long term results of percutaneous coronary intervention with the useof drug eluting balloon in patients with coronary artery disease


Introduction Since the 1970's, when the first percutaneous coronary intervention (PCI) wasperformed, this method has undergone a distinct evolution. In turn the effectiveaction of locally administered drugs has contributed to the development of theconcept of a antimitotic drug-eluting balloon (DEB).AimsThe goal of this study was to analyze the long-term results of PCI with DEB incorrelation with the clinical and angiographic characteristics of the treated patientsand the treatment strategy.ResultsA total of 112 patients were included in the study. The population was thendivided into two groups, A (40%) consisted of patients with target vessel failure(TVF), B (60%) without TVF. The study group was comprised mainly of patients inthe sixth decade of life that had been qualified for the invasive treatment of unstableangina. Male patients dominated. More than half of the patients were active smokerswith a history of myocardial infarction.The differences between study groups were observed in relation to the followingfactors: differences in severity of heart failure (NYHA III and IV A 32%, B 13%,p=0.0479), previous PCI (A 19.4%, B 4.3%, p=0.0423), treated lesion length (A19.4 mm, B 16.1 mm, p=0.0166), predilatation with standard balloon (A 60%, B33%, p=0.0119), residual stenosis (A 20%, B 17%, p=0.0341).Regression model showed independent risk factors affecting the prognosis:severity of heart failure (p = 0.0250; OR 1.34-33.23) and initial length of the treatedlesion (p = 0.0273, OR 1.02-1.30)ConclusionsPCI with the use of a DEB is a safe method to treat patients diagnosed withischemic heart disease. The results of investigated strategy can be significantly betterin the treatment of shorter lesions in patients without signs of heart failure, and inthis group should be taking into consideration, especially in case of contraindicationsfor DES.

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Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia ; kardiochirurgia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.


Krzysztof Żmudka

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tylko w bibliotece

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Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

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Last modified:

Jun 26, 2019

In our library since:

Jan 9, 2014

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Edition name Date
ZB-119608 Jun 26, 2019


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