Title:

Analysis of selected risk factors for adenoma recurrence in patients after endoscopic polypectomy of the large intestine

Author:

Pędziwiatr, Michał Jan.

Subject:

adenoma ; large intestine ; colonoscopy ; recurrence ; polypectomy

Abstract:

In certain patients despite of the removal of all adenomas new lesions appear. Additionally there is a group of patients at a greater risk of developing new polyps. The aim of this study was to analyse recurrence rate of new adenomas in surveillance colonoscopy in patients after polypectomy. A group of 184 patients who underwent endoscopic polypectomy and surveillance colonoscopy were involved in the analysis. Histopathological features of primarily removed adenomas as well as recurrent polyps were evaluated. Further aspect of the study was the identification of risk factors that may have led to increased recurrence rate of adenomas. The most common pathomorphological type of removed adenomas was tubular with medium grade dysplasia. Average size of polyps was 9,6 mm. Primary lesions were mostly found in the sigmoid and rectum. Reappearance of new colorectal polyps was 38%. In the majority of cases recurrent adenomas were smaller (6,1mm) than the initial ones. Most of them were of tubular type with low-grade dysplasia. They were more commonly seen in the proximal parts of the colon. Male gender, smoking, statins, removal of more than one polyp, initial lesions in the proximal colon, size over 10mm, high-grade dysplasia or advanced adenoma seemed to influence the risk of recurrence. In our opinion patients with the before mentioned characteristics are at increased risk of polyp recurrence.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree discipline:

chirurgia

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Kazimierz Rembiasz

Date:

2013

Date issued:

2013

Type:

Praca doktorska

Format:

application/pdf

Call number:

ZB-119113

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Language:

pol

Access rights:

nieograniczony

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

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