Advanced search ?

Object

Access Limited

This publication is protected and available only for logged users.
This publication is protected and available only for logged users.

Title: The role of endothelium and disturbances of blood flowautoregulationin the pathogenesis of reflex syncope

Author:

Wnuk, Mateusz.

Date:

2012

Type:

Praca doktorska

Abstract:

The aim of the study was to evaluate: the role of endothelial function in thepathogenesis of vasovagal syncope (VVS) using flow-mediated dilation (FMD) andendothelium-independent dilation (EID); the significance of FMD and EID aspredictive factors of VVS during head-up tilt test (HUTT); the relationship betweenFMD and EID and the type of response to orthostatic stress according to VASIScriteria; the usefulness of ultrasonographic parameters calculated from the pulsedDoppler velocity signal obtained during the study of FMD and EID: maximumvelocity (Vmax), minimum velocity (Vmin), end-diastolic velocity (EDV), timeaveraged maximum velocity (TAMX), pulsatility index (PI) and resistance index (RI)in diagnosis of reflex syncope. The study comprised 80 subjects: gr. A: 50 pts withVVS, aged 17-39 yrs (mean 26.6±7.5), including 39 (78%) women and gr. K: 30subjects without VVS, aged 17-40 yrs (mean 29.7±5.7) including 23 (76.7%)women. Values of FMD and EID in pts with VVS were significantly greater thanthose in controls. It may point that the augmented endothelial function plays animportant role in VVS. The cut-off points for FMD ≥ 10,49% and for EID ≥ 27.64%were predicting syncope occurrence during HUTT with sensitivity respectivly: 100%and 64.6% and specificity: 87.5% both for FMD and EID. Independent predictors ofVVS occurrence during HUTT were: FMD, EDV during D2 phase of FMD and EIDassessment and DBP in supine position. It was not demonstrated any importantrelationship between the type of response to orthostatic stress according to VASIScriteria and values of FMD, EID and the differrences between PI and RI indices.

Place of publishing:

Kraków

Level of degree:

2 - studia doktoranckie

Degree grantor:

Uniwersytet Jagielloński. Collegium Medicum. Wydział Lekarski.

Promoter:

Wiesława Piwowarska

Date issued:

2012

Format:

application/pdf

Identifier:

oai:dl.cm-uj.krakow.pl:3493

Call number:

ZB-117821

ControlNumberVIRTUA:

click here to follow the link

Language:

pol

Access rights:

tylko w bibliotece

Location of original object:

Biblioteka Medyczna Uniwersytetu Jagiellońskiego- Collegium Medicum

Subject and keywords:

reflex syncope endothelium FMD EID nitric oxide

Object collections:

Last modified:

Oct 28, 2019

In our library since:

Mar 25, 2013

Number of object content hits:

1

Number of object content views in PDF format

1

All available object's versions:

http://dl.cm-uj.krakow.pl:8080/publication/3493

Show description in RDF format:

RDF

Show description in OAI-PMH format:

OAI-PMH

Edition name Date
ZB-117821 Oct 28, 2019

Objects

Similar

The role of endothelium and disturbances of blood flowautoregulationin the pathogenesis of reflex syncope

Wnuk, Mateusz.

2012
Praca doktorska

Endothelial function in atrial fibrillation

Rewiuk, Krzysztof.

2014
Praca doktorska

Endothelial dysfunction in systemie connective tissue diseases

Pacholczak, Renata

2019
Praca doktorska

Role of vascular endothelial adaptation in regulation of exercise capacity, platelet activation and post-exercise endothelial function in mice

Przyborowski, Kamil

2019
Praca doktorska

Correlation between polimorfizm of GTP cyclohydrolase 1 and endothelial dysfunction in patients with type 2 diabetes

Kosiniak-Kamysz, Władysław

2010
Praca doktorska

Coronary endothelial dysfunction in heart failure in Tg[alfa]q*44 mice

Drelicharz, Łukasz

2006
Praca doktorska

Relationship between selected polymorphisms of gene encoding p22phox subunit of the NADPH oxidase and endothelial function in patients with type 2 diabetes

Osmenda, Grzegorz

2007
Praca doktorska

Effect of fenofibrate therapy on brachial artery diastolic response, and plasma N1-methylnicotinamide, and homocysteine concentrations in the subjects with dyslipidemia

Kotula-Horowitz, Katarzyna

2020
Praca doktorska
More
×

Citation

Citation style:

Contact details

Address

Medical Library
Medyczna 7
30-688 Krakow

Phone

12 658 72 56
517 385 669

E-Mail

Collecting and Elaboration Department
cyfrowabm@cm-uj.krakow.pl

Visit us!

This page uses 'cookies'. More information