Title: Response to CRT in patient with chronic heart failure depending on the ventricular leads localization


The aim of the study was to assess how the response to CRT depends on ventricle leads localization, usefulness of radiological methods in prediction response to CRT and examination influence modified stimulator’s parameters on response to CRT. 50 consequence patients after CRT implantation were enrolled to the study. Horizontal separation was larger in the group of the patients who died (9,0 ± 1.8 cm vs 8,0 ±3,2 cm, p=0,0222). Significant correlation between LV lead’s segment in AP chest X-ray and LVESV was observed (r = 0,75, p = 0,030). Significant correlation between right lead segment in AP projection and narrowing of the QRS complex as well as change of LVESV were observed (r = -0,46, p = 0,022; r = -0,74, p = 0,037, ). In the lateral chest X-ray RV lead’s segment correlated with change of the QRS complex (r = -0,51, p = 0,010). There was correlation between narrowing of the QRS complex and absolute separation (r = -0,42, p = 0,036) and horizontal separation (r = -0,41, p = 0,044). LV EF increase was larger when RV lead was located in line 2 comparising to localization in line 3 or 4 (45,12 ± 28,5% vs 18,1 ± 31,6%, p = 0,0406), whereas QRS was narrower for line 3 and 4 comparising to line 2 (-19,3 ± 13,7 ms vs -6,8 ± 10,0 ms, p = 0.0122). Mean value of the left ventricle segment was higher in patient with decreased NT-proBNP plasma concentration (13,4 ± 2,4 vs 8,3 ± 2,3, p ; =0,036). 6-MWT distance was longer in the group with increased AV-delay (22,2 ± 15,4 % vs -10,1 ±29%, p = 0,0045). Conclusion: radiological methods of localization of the ventricular leads are a useful tool in prediction response to CRT, but results are ambiguous.

Place of publishing:


Level of degree:

2 - studia doktoranckie

Degree discipline:

choroby układu krążenia

Degree grantor:

Wydział Lekarski


Czarnecka, Danuta

Date issued:




Call number:




Access rights:


Object collections:

Last modified:

Mar 14, 2023

In our library since:

Mar 7, 2013

Number of object content hits:


Number of object content views in PDF format


All available object's versions:


Show description in RDF format:


Show description in OAI-PMH format:


Edition name Date
ZB-117135 Mar 14, 2023


Citation style:

This page uses 'cookies'. More information