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Title: Influence of selected prognostic factors on treatment results invulvar cancer
Abstract:
OBJECTIVES The aim of the study is to determine the relationship between selected prognostic factors and the presence of lymph node metastases and treatment results as well as to compare the surgical treatment in the years 1978-1990 and 1991-2004 in vulvar cancer. MATERIAL AND METHODS The study group consisted of 171 female patients treated surgically in 1978-1990 and 174 in 1991-2004. The relationship between the morphological form, histological differentiation level, location, the depth of invasion and the presence of lymph node metastases and their influence on the recurrence and 3-and 5-year survival. The study evaluated also the impact of the change in therapeutic procedure on the treatment results in1991-2004. RESULTS There was a statistically significant increase of metastases in lymph nodes related to the stage, the increase of the depth of invasion, in a basaloid form, in G1. The recurrence ratio increased significantly with the stage, lymph nodes metastases, in G3, with the central location and a basaloid form. Statistically significant decline in survival rate was observed with the stage, in G3, with the central location, in patients over 60, in lymph nodes metastases. The reduction of the radical character of the surgery at stage I and partly at stage II did not affect negatively the treatment outcomes. CONCLUSIONS The most important prognostic factors are: lymph no ; de metastases, stage, histological differentiation and age. The incidence of lymph node metastases increases with the stage, depth of tumor invasion, in G3, in a basaloid form. Limiting the surgery did not affect negatively the treatment outcomes.
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Last modified:
Mar 17, 2023
In our library since:
Mar 7, 2013
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9
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http://dl.cm-uj.krakow.pl:8080/publication/3441
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| Edition name | Date |
|---|---|
| ZB-116311 | Mar 17, 2023 |
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